ReviewGeburtshilfe und Frauenheilkunde2011
Circulating Tumor Cells in Early-Stage Breast Cancer.
Review in Geburtshilfe und Frauenheilkunde, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Article
- Proof-of-principle study usingJournal of biosciences · 2024Article
- Correlation between Imaging Markers Derived from PET/MRI and Invasive Acquired Biomarkers in Newly Diagnosed Breast Cancer.Cancers · 2023Article
- Comparison of RNA Marker Panels for Circulating Tumor Cells and Evaluation of Their Prognostic Relevance in Breast Cancer.Cancers · 2023Article
- Radiogenomics, Breast Cancer Diagnosis and Characterization: Current Status and Future Directions.Methods and protocols · 2022Review
- The Role of Circulating Tumor Cells in Chemoresistant Metastatic Breast Cancer.Journal of clinical medicine · 2021Review
- How to Predict Metastasis in Luminal Breast Cancer? Current Solutions and Future Prospects.International journal of molecular sciences · 2020Review
- An automated high-throughput counting method for screening circulating tumor cells in peripheral blood.Analytical chemistry · 2013Article
- Participation in the SUCCESS-A Trial Improves Intensity and Quality of Care for Patients with Primary Breast Cancer.Geburtshilfe und Frauenheilkunde · 2013Article
- Advances in Breast Cancer - Looking Back over the Year.Geburtshilfe und Frauenheilkunde · 2012Article
- Sentinel Lymph Node Biopsy in Patients with Breast Cancer: Comparison of Peritumoral and Periareolar Injection.Geburtshilfe und Frauenheilkunde · 2012Article
- Re-excision Rates and Local Recurrence in Breast Cancer Patients Undergoing Breast Conserving Therapy.Geburtshilfe und Frauenheilkunde · 2012Article
- Chemotherapy-Induced Amenorrhea - An Update.Geburtshilfe und Frauenheilkunde · 2012Article
- Breast Cancer: State of the Art and New Findings.Geburtshilfe und Frauenheilkunde · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Disseminated tumor cells (DTC) are routinely detected in bone marrow (BM) in 30-40 % of primary breast cancer patients. Positive BM status at the time of diagnosis as well as DTC persistence after therapy are strong independent prognostic factors. Since repeated BM aspirations are not well tolerated, detection of single tumor cells in peripheral blood (circulating tumor cells; CTC) have become of interest in recent years. CTC are found in 10-80 % breast cancer patients. Variability can be explained by stage of the disease and detection method. Emerging data have shown CTC to be of prognostic relevance for both, patients with primary and metastatic disease. The assessment of CTC in blood may become an important biomarker for prognostication and therapy monitoring. Determination of their molecular characteristics will enable specific targeting of minimal residual as well as metastatic disease. This review summarizes recent research and future perspectives.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.