Evidence map›Paper›PMID 28434825›Full record

ReviewStem cell research2017

RNA-binding proteins in human oogenesis: Balancing differentiation and self-renewal in the female fetal germline.

Roseanne Rosario, Andrew J Childs, Richard A Anderson

Abstract readReview
In one paragraph

Review in Stem cell research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Oocyte development: it's all about quality.Reproductive biomedicine online · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. ADR-2 regulates fertility and oocyte fate inbioRxiv : the preprint server for biology · 2024
    Article
  9. Review
  10. Review
  11. The APC/CFrontiers in cell and developmental biology · 2021
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Being a good egg in the 21st century.British medical bulletin · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Roseanne RosarioMRC Centre for Reproductive Health, Queen's Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.
Andrew J ChildsDepartment of Comparative Biomedical Sciences, The Royal Veterinary College, London NW1 0TU, UK.
Richard A AndersonMRC Centre for Reproductive Health, Queen's Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK. Electronic address: richard.anderson@ed.ac.uk.

Funding

Medical Research Council G1002118Medical Research Council G1100357
6 · The paper itself

Abstract

Primordial germ cells undergo three significant processes on their path to becoming primary oocytes: the initiation of meiosis, the formation and breakdown of germ cell nests, and the assembly of single oocytes into primordial follicles. However at the onset of meiosis, the germ cell becomes transcriptionally silenced. Consequently translational control of pre-stored mRNAs plays a central role in coordinating gene expression throughout the remainder of oogenesis; RNA binding proteins are key to this regulation. In this review we examine the role of exemplars of such proteins, namely LIN28, DAZL, BOLL and FMRP, and highlight how their roles during germ cell development are critical to oogenesis and the establishment of the primordial follicle pool.

Indexed as

Cell DifferentiationCell Self RenewalOogenesisFemaleFetusGerm CellsHumansRNA-Binding ProteinsRNA-Binding ProteinsBOLLDAZLFMRPGerm cell differentiationLIN28RNA binding proteins

Identifiers

PMID28434825
PMCPMC5446320

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.