Evidence map›Paper›PMID 28434109›Full record

ReviewCurrent obesity reports2017

Insights into the Link Between Obesity and Cancer.

Sarah E Ackerman, Olivia A Blackburn, François Marchildon, Paul Cohen

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current obesity reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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  6. Obesity in adults: a clinical practice guideline.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2020 · on this map
    Guideline
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3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sarah E AckermanLaboratory of Molecular Metabolism, The Rockefeller University, New York, NY, USA.
Olivia A BlackburnLaboratory of Molecular Metabolism, The Rockefeller University, New York, NY, USA.
François MarchildonLaboratory of Molecular Metabolism, The Rockefeller University, New York, NY, USA.
Paul CohenLaboratory of Molecular Metabolism, The Rockefeller University, New York, NY, USA. pcohen@rockefeller.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewAdipocytes have adapted to store energy in the form of lipid and also secrete circulating factors called adipokines that signal to other tissues to coordinate energy homeostasis. These functions are disrupted in the setting of obesity, promoting the development of diseases such as diabetes, cardiovascular disease, and cancer. RECENT

findingsObesity is linked to an increased risk of many types of cancer and increased cancer-related mortality. The basis for the striking association between obesity and cancer is not well understood. Here, we review the cellular and molecular pathways that appear to be involved in obesity-driven cancer. We also describe possible therapeutic considerations and highlight important unanswered questions in the field.

Indexed as

Energy MetabolismAdipocytesAdipokinesAnimalsAntineoplastic AgentsComorbidityCytokinesDrug RepositioningHumansHypoglycemic AgentsHypolipidemic AgentsInflammation MediatorsInsulinNeoplasmsObesityRisk FactorsAdipokinesAntineoplastic AgentsCytokinesHypoglycemic AgentsHypolipidemic AgentsInflammation MediatorsInsulinSomatomedinsAdipocyteAdipokineAdiponectinCancerLeptinMetastasisObesityTumor microenvironment

Identifiers

PMID28434109

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.