Evidence map›Paper›PMID 28434063›Full record

ArticleJournal of fluorescence2017

Constrained Photophysics of 5,7-dimethoxy-2,3,4,9-tetrahydro-1H-carbazol-1-one in the Bioenvironment of Serum Albumins: A Spectroscopic Endeavour Supported by Molecular Docking Analysis.

Amrit Krishna Mitra, Abhishek Sau, Uttam Pal, Chandan Saha, Samita Basu

Abstract read
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In one paragraph

Article in Journal of fluorescence, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Amrit Krishna MitraDepartment of Chemistry, Government General Degree College, Singur, Hooghly, West Bengal, Pin:712409, India.
Abhishek SauChemical Sciences Division, Saha Institute of Nuclear Physics, Kolkata, 700064, India.
Uttam PalChemical Sciences Division, Saha Institute of Nuclear Physics, Kolkata, 700064, India.
Chandan SahaDepartment of Clinical and Experimental Pharmacology, School of Tropical Medicine, Kolkata, 700073, India.
Samita BasuChemical Sciences Division, Saha Institute of Nuclear Physics, Kolkata, 700064, India. samita.basu@saha.ac.in.
Saha Institute of Nuclear Physics · INGovernment of West Bengal · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper vividly indicates that steady state as well as time-resolved fluorescence techniques can serve as highly sensitive monitors to explore the interactions of 5,7-dimethoxy-2,3,4,9-tetrahydro-1H-carbazol-1-one with model transport proteins, bovine serum albumin (BSA) and human serum albumin (HSA). Besides these, we have used fluorescence anisotropy study to assess the degree of restrictions imparted by the micro-environments of serum albumins. Again, to speculate the triplet excited state interaction between such fluorophore and albumin proteins (BSA& HSA), laser flash-photolysis experiments have been carried out. Molecular docking experiments have also been performed to support the conclusions obtained from steady state experiments.

Indexed as

LasersMolecular Docking SimulationPhotolysisAnimalsCarbazolesCattleFluorescenceFluorescent DyesHumansProtein BindingSerum AlbuminSerum Albumin, BovineSpectrometry, FluorescenceThermodynamicsCarbazolesFluorescent DyesSerum AlbuminSerum Albumin, BovineFluorescence anisotropyKeto-tetrahydrocarbazoleLaser flash photolysisMolecular dockingSerum albumin

Identifiers

PMID28434063
OpenAlexW2606771744

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.