Evidence map›Paper›PMID 28434059›Full record

Observational studyLangenbeck's archives of surgery2017

Early warning score independently predicts adverse outcome and mortality in patients with acute pancreatitis.

Michael J Jones, Christopher P Neal, Wee Sing Ngu, Ashley R Dennison, Giuseppe Garcea

Abstract readObservational Study
In one paragraph

Observational study in Langenbeck's archives of surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. B Cells and Double-Negative B Cells (CD27Diseases (Basel, Switzerland) · 2024
    Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Michael J JonesDepartment of Hepatobiliary Surgery, University Hospitals of Leicester, Leicester, LE5 4PW, UK.
Christopher P NealDepartment of Hepatobiliary Surgery, University Hospitals of Leicester, Leicester, LE5 4PW, UK. cpn3@leicester.ac.uk.
Wee Sing NguDepartment of Hepatobiliary Surgery, University Hospitals of Leicester, Leicester, LE5 4PW, UK.
Ashley R DennisonDepartment of Hepatobiliary Surgery, University Hospitals of Leicester, Leicester, LE5 4PW, UK.
Giuseppe GarceaDepartment of Hepatobiliary Surgery, University Hospitals of Leicester, Leicester, LE5 4PW, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to compare the prognostic value of established scoring systems with early warning scores in a large cohort of patients with acute pancreatitis.

methodsIn patients presenting with acute pancreatitis, age, sex, American Society of Anaesthesiologists (ASA) grade, Modified Glasgow Score, Ranson criteria, APACHE II scores and early warning score (EWS) were recorded for the first 72 h following admission. These variables were compared between survivors and non-survivors, between patients with mild/moderate and severe pancreatitis (based on the 2012 Atlanta Classification) and between patients with a favourable or adverse outcome.

resultsA total of 629 patients were identified. EWS was the best predictor of adverse outcome amongst all of the assessed variables (area under curve (AUC) values 0.81, 0.84 and 0.83 for days 1, 2 and 3, respectively) and was the most accurate predictor of mortality on both days 2 and 3 (AUC values of 0.88 and 0.89, respectively). Multivariable analysis revealed that an EWS ≥2 was independently associated with severity of pancreatitis, adverse outcome and mortality.

conclusionThis study confirms the usefulness of EWS in predicting the outcome of acute pancreatitis. It should become the mainstay of risk stratification in patients with acute pancreatitis.

Indexed as

Acute DiseaseAdolescentAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedPancreatitisPredictive Value of TestsPrognosisRetrospective StudiesSeverity of Illness IndexTreatment OutcomeAcute pancreatitisEWSMortalityOutcomeScoring

Identifiers

PMID28434059
PMCPMC5506178

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.