ArticleJournal of chromatography. B, Analytical technologies in the biomedical and life sciences2017
High sensitivity HPLC method for analysis of in vivo extracellular GABA using optimized fluorescence parameters for o-phthalaldehyde (OPA)/sulfite derivatives.
Article in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 30 citations in OpenAlex.
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- Reversal of diabetes-associated cognitive impairment through modulation of BDNF, insulin, and NF-κB pathways by a marketed herbal formulation.3 Biotech · 2026Article
- 1,3,4 oxadiazole derivative attenuates neurotransmitter-mediated inflammatory response in EAE model of multiple sclerosis.Scientific reports · 2026Article
- Elucidating the role of compatible solutes in growth protection and amelioration of oxidative stress in the thermophilic cyanobacterium Mastigocladus sp. TA-8 during temperature shifts.Extremophiles : life under extreme conditions · 2025Article
- Effect of Plastein Reaction on Physical and Chemical Characteristics of Corn Glutelin Peptides and Quality of Chiffon Cake.Foods (Basel, Switzerland) · 2025Article
- Time-course concentration of ethanol, acetaldehyde and acetate in rat brain dialysate following alcohol self-administration.Alcohol (Fayetteville, N.Y.) · 2025Article
- Quantitation of Vaporized γ-Aminobutyric Acid in Cigarette Smoke Extract From e-Cigarettes by the Combination of HPLC-Fluorescence Detection and Derivatization With DBD-F.Luminescence : the journal of biological and chemical luminescence · 2024Article
- Experimental and numerical investigation of microdialysis probes for ethanol metabolism studies.Analytical methods : advancing methods and applications · 2024Article
- Parametric study of a microdialysis probe and study of depletion effect using ethanol as a test analyte.Biochemical and biophysical research communications · 2022Article
- Effects of sustained GABA releasing implants on pancreatic islets in mice.Drug delivery and translational research · 2021Article
- Reduced Activation of the Synaptic-Type GABAMolecular pharmacology · 2020Article
- Steady-state activation of the high-affinity isoform of the α4β2δ GABAScientific reports · 2019Article
- Efficient synthesis of 4-substituted-Beilstein journal of organic chemistry · 2019Article
- Infrared spectroscopy for neurochemical monitoring of alcohol and its metabolites.Proceedings of SPIE--the International Society for Optical EngineeringArticle
Corrections and comments
- Erratum issued
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Reversed-phase HPLC with derivatization using o-phthalaldehyde (OPA) and sulfite allows electrochemical detection of γ-aminobutyric acid (GABA) in microdialysis samples. However, OPA/sulfite derivatives have been reported to produce lower fluorescent yield than OPA derivatives using organic thiols as the nucleophile. To overcome this limitation we examined excitation and emission spectra, reaction time, pH, and concentration of reagents in the derivatization solution. Optimal detection parameters were determined as λ
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Registered trials
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