Evidence map›Paper›PMID 28433729›Full record

ArticleTicks and tick-borne diseases2017

Comparative vertical transmission of Rickettsia by Dermacentor variabilis and Amblyomma maculatum.

Emma K Harris, Victoria I Verhoeve, Kaikhushroo H Banajee, Jacqueline A Macaluso, Abdu F Azad, Kevin R Macaluso

Abstract read
In one paragraph

Article in Ticks and tick-borne diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Article
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  7. Critical roles ofInfection and immunity · 2024
    Article
  8. Identification and characterization of a Relish-type NF-κB, DvRelish, inFrontiers in cellular and infection microbiology · 2024
    Article
  9. Frontiers in immunology · 2023
    Article
  10. Current Data onMicroorganisms · 2022
    Article
  11. Analysis of the Type 4 Effectome across the GenusInternational journal of molecular sciences · 2022
    Article
  12. Review
  13. Article
  14. Culture Isolate ofInternational journal of environmental research and public health · 2022
    Article
  15. What do we know about the microbiome ofFrontiers in cellular and infection microbiology · 2022
    Review
  16. Review
  17. Review
  18. Article
  19. Frontiers in microbiology · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Emma K HarrisVector-Borne Disease Laboratories, Department of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Skip Bertman Dr., SVM-3213, Baton Rouge, LA, 70803, USA.
Victoria I VerhoeveVector-Borne Disease Laboratories, Department of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Skip Bertman Dr., SVM-3213, Baton Rouge, LA, 70803, USA.
Kaikhushroo H BanajeeVector-Borne Disease Laboratories, Department of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Skip Bertman Dr., SVM-3213, Baton Rouge, LA, 70803, USA.
Jacqueline A MacalusoDepartment of Microbiology and Immunology, School of Medicine, University of Maryland, 685 W. Baltimore St., HSF I Suite 380, Baltimore, MD, 21201, USA.
Abdu F AzadDepartment of Microbiology and Immunology, School of Medicine, University of Maryland, 685 W. Baltimore St., HSF I Suite 380, Baltimore, MD, 21201, USA.
Kevin R MacalusoVector-Borne Disease Laboratories, Department of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Skip Bertman Dr., SVM-3213, Baton Rouge, LA, 70803, USA. Electronic address: kmacal2@lsu.edu.

Funding

MURINE TYPHUS: VECTOR BIOLOGY AND TRANSMISSIONR01AI017828 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI RAHMAN, MOHAMMED SAYEEDUR · 1985 to 2022
$10.2M
Emerging Flea-Borne Rickettsial Diseases: vector competence and transmission biologyR01AI122672 · NIAID · UNIVERSITY OF SOUTH ALABAMA · PI MACALUSO, KEVIN R. · 2016 to 2025
$4.2M
Murine Typhus: Vector Biology &TransmissionR37AI017828 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI AZAD, ABDU F · 1998 to 2007
$3.6M
Molecular basis for spotted fever group Rickettsia vector competence in ticksR01AI077784 · NIAID · UNIVERSITY OF SOUTH ALABAMA · PI MACALUSO, KEVIN R. · 2009 to 2019
$3.5M
INTERSPECIFIC COMPETITION BETWEEN RICKETTSIAE IN TICKSR01AI043006 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI AZAD, ABDU F · 1998 to 2014
$3.3M
Research Training in Experimental Medicine and PathologyT32OD011124 · OD · TULANE UNIVERSITY OF LOUISIANA · PI BLAIR, ROBERT, RAPPAPORT, JAY · 2012 to 2019
$2.7M
NIAID NIH HHS R01 AI017828NIAID NIH HHS R01 AI043006NIAID NIH HHS R01 AI077784NIAID NIH HHS R01 AI122672NIAID NIH HHS R37 AI017828NIH HHS T32 OD011124
6 · The paper itself

Abstract

The geographical overlap of multiple Rickettsia and tick species coincides with the molecular detection of a variety of rickettsial agents in what may be novel tick hosts. However, little is known concerning transmissibility of rickettsial species by various tick hosts. To examine the vertical transmission potential between select tick and rickettsial species, two sympatric species of ticks, Dermacentor variabilis and Amblyomma maculatum, were exposed to five different rickettsial species, including Rickettsia rickettsii, Rickettsia parkeri, Rickettsia montanensis, Rickettsia amblyommatis, or flea-borne Rickettsia felis. Fitness-related metrics including engorgement weight, egg production index, nutrient index, and egg hatch percentage were then assessed. Subsamples of egg clutches and unfed larvae, nymphs, and adults for each cohort were assessed for transovarial and transstadial transmission of rickettsiae by qPCR. Rickettsial exposure had a minimal fitness effect in D. variabilis and transovarial transmission was observed for all groups except R. rickettsii. In contrast, rickettsial exposure negatively influenced A. maculatum fitness and transovarial transmission of rickettsiae was demonstrated only for R. amblyommatis- and R. parkeri-exposed ticks. Sustained maintenance of rickettsiae via transstadial transmission was diminished from F

Indexed as

Infectious Disease Transmission, VerticalAnimalsDermacentorFeeding BehaviorFemaleIxodidaeLarvaMaleNymphRatsRats, Sprague-DawleyRickettsiaRickettsia InfectionsAmblyommaDermacentorRickettsiaVertical transmission

Identifiers

PMID28433729
PMCPMC5702269

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.