ArticleJournal of the American Academy of Child and Adolescent Psychiatry2017
Paternal Age Alters Social Development in Offspring.
Article in Journal of the American Academy of Child and Adolescent Psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed.
- Elevated zygotic let-7f-5p alters developmental trajectories and sex-specific somatic growth.iScience · 2026Article
- Children with a history of both maternal immune activation and prematurity are not at increased risk of ADHD symptoms.European child & adolescent psychiatry · 2024Article
- Building a family at advanced parental age: a systematic review on the risks and opportunities for parents and their offspring.Human reproduction open · 2023Review
- Family, personal, parental correlates and behavior disturbances in school-aged boys with attention-deficit/hyperactivity disorder (ADHD): a cross-sectional study.Child and adolescent psychiatry and mental health · 2022Article
- The Association Between Parental Age and Autism-Related Outcomes in Children at High Familial Risk for Autism.Autism research : official journal of the International Society for Autism Research · 2020Article
- Paternal age in rhesus macaques is positively associated with germline mutation accumulation but not with measures of offspring sociability.Genome research · 2020Article
- Parental Age and Offspring Childhood Mental Health: A Multi-Cohort, Population-Based Investigation.Child development · 2020Article
- Paternal age is affected by genetic abnormalities, perinatal complications and mental health of the offspring.Biomedical reports · 2020Article
- Parental Age and Differential Estimates of Risk for Neuropsychiatric Disorders: Findings From the Danish Birth Cohort.Journal of the American Academy of Child and Adolescent Psychiatry · 2019Article
- Prenatal Risk for ASD: Fetal Cortisol Exposure Predicts Child Autism-Spectrum Disorder Symptoms.Clinical psychological science : a journal of the Association for Psychological Science · 2019Article
- Widespread covariation of early environmental exposures and trait-associated polygenic variation.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Advantageous developmental outcomes of advancing paternal age.Translational psychiatry · 2017Article
- The Role of Paternal Age in the Prediction of Offspring Intelligence.The Journal of genetic psychologyArticle
Corrections and comments
- Erratum issuedCorrigendum.2017
Authors and funding
10 authors.
Funding
Abstract
objectiveAdvanced paternal age (APA) at conception has been linked with autism and schizophrenia in offspring, neurodevelopmental disorders that affect social functioning. The current study explored the effects of paternal age on social development in the general population.
methodWe used multilevel growth modeling to investigate APA effects on socioemotional development from early childhood until adolescence, as measured by the Strengths and Difficulties Questionnaire (SDQ) in the Twins Early Development Study (TEDS) sample. We also investigated genetic and environmental underpinnings of the paternal age effects on development, using the Additive genetics, Common environment, unique Environment (ACE) and gene-environment (GxE) models.
resultsIn the general population, both very young and advanced paternal ages were associated with altered trajectory of social development (intercept: p = .01; slope: p = .03). No other behavioral domain was affected by either young or advanced age at fatherhood, suggesting specificity of paternal age effects. Increased importance of genetic factors in social development was recorded in the offspring of older but not very young fathers, suggesting distinct underpinnings of the paternal age effects at these two extremes.
conclusionOur findings highlight that the APA-related deficits that lead to autism and schizophrenia are likely continuously distributed in the population.
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