Evidence map›Paper›PMID 28433050›Full record

ReviewAdvances in virus research2017

Zoonotic Potential of Emerging Paramyxoviruses: Knowns and Unknowns.

Patricia A Thibault, Ruth E Watkinson, Andres Moreira-Soto, Jan F Drexler, Benhur Lee

Open access · greenAbstract readReview
In one paragraph

Review in Advances in virus research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed
32.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed, 115 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
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  6. Paramyxoviruses in Bats in Poland-The First Detection.Pathogens (Basel, Switzerland) · 2026
    Article
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  8. Review
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  13. Review
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  18. Article
  19. A universal design of restructured dimer antigens: Development of a superior vaccine against the paramyxovirus in transgenic rice.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  20. Article

18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Patricia A ThibaultIcahn School of Medicine at Mount Sinai, New York, NY, United States.
Ruth E WatkinsonIcahn School of Medicine at Mount Sinai, New York, NY, United States.
Andres Moreira-SotoInstitute of Virology, University of Bonn Medical Centre, Bonn, Germany.
Jan F DrexlerInstitute of Virology, University of Bonn Medical Centre, Bonn, Germany; German Centre for Infection Research (DZIF), Partner Site Bonn-Cologne, Bonn, Germany.
Benhur LeeIcahn School of Medicine at Mount Sinai, New York, NY, United States. Electronic address: benhur.lee@mssm.edu.
Icahn School of Medicine at Mount Sinai · USUniversity of Bonn · DE

Funding

Tropism, pathogenicity, and potential for zoonotic spillover of emergent henipa- and henipa-like virusesR01AI123449 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI LEE, BENHUR · 2016 to 2020
$2.7M
NIAID NIH HHS R01 AI123449
6 · The paper itself

Abstract

The risk of spillover of enzootic paramyxoviruses and the susceptibility of recipient human and domestic animal populations are defined by a broad collection of ecological and molecular factors that interact in ways that are not yet fully understood. Nipah and Hendra viruses were the first highly lethal zoonotic paramyxoviruses discovered in modern times, but other paramyxoviruses from multiple genera are present in bats and other reservoirs that have unknown potential to spillover into humans. We outline our current understanding of paramyxovirus reservoir hosts and the ecological factors that may drive spillover, and we explore the molecular barriers to spillover that emergent paramyxoviruses may encounter. By outlining what is known about enzootic paramyxovirus receptor usage, mechanisms of innate immune evasion, and other host-specific interactions, we highlight the breadth of unexplored avenues that may be important in understanding paramyxovirus emergence.

Indexed as

PhylogenyAnimalsCatsChiropteraDisease ResistanceDisease SusceptibilityDisease VectorsDogsHost-Pathogen InteractionsHumansParamyxoviridae InfectionsParamyxovirinaeRodentiaZoonosesEcologyEmerging virusesHenipavirusMorbillivirusParamyxovirusPathogenesisReservoirRubulavirusTropismZoonotic

Identifiers

PMID28433050
PMCPMC5894875
OpenAlexW2584434289

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.