Evidence map›Paper›PMID 28432790›Full record

ArticleeLife2017

Single-molecule visualization of fast polymerase turnover in the bacterial replisome.

Jacob S Lewis, Lisanne M Spenkelink, Slobodan Jergic, Elizabeth A Wood, Enrico Monachino, Nicholas P Horan, Karl E Duderstadt, Michael M Cox, Andrew Robinson, Nicholas E Dixon and 1 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

82 citing papers in PubMed, 128 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Genome integrity relies on rapid recycling of DNA Pol III in bacteria.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. A bipartite interaction with the processivity clamp potentiates Pol IV-mediated TLS.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Review

22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 4 countries.

Jacob S LewisCentre for Medical and Molecular Bioscience, University of Wollongong, Wollongong, Australia.ORCID 0000-0002-9945-6133
Lisanne M SpenkelinkCentre for Medical and Molecular Bioscience, University of Wollongong, Wollongong, Australia.ORCID 0000-0002-5511-8757
Slobodan JergicCentre for Medical and Molecular Bioscience, University of Wollongong, Wollongong, Australia.
Elizabeth A WoodDepartment of Biochemistry, University of Wisconsin-Madison, Madison, United States.
Enrico MonachinoCentre for Medical and Molecular Bioscience, University of Wollongong, Wollongong, Australia.
Nicholas P HoranCentre for Medical and Molecular Bioscience, University of Wollongong, Wollongong, Australia.
Karl E DuderstadtZernike Institute for Advanced Materials, University of Groningen, Groningen, The Netherlands.
Michael M CoxDepartment of Biochemistry, University of Wisconsin-Madison, Madison, United States.
Andrew RobinsonCentre for Medical and Molecular Bioscience, University of Wollongong, Wollongong, Australia.
Nicholas E DixonCentre for Medical and Molecular Bioscience, University of Wollongong, Wollongong, Australia.ORCID 0000-0002-5958-6945
Antoine M van OijenCentre for Medical and Molecular Bioscience, University of Wollongong, Wollongong, Australia.ORCID 0000-0002-1794-5161
University of Wollongong · AUUniversity of Groningen · NLUniversity of Wisconsin–Madison · US

Funding

THE BIOCHEMISTRY OF GENETIC RECOMBINATION/RECA PROTEINR01GM032335 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI COX, MICHAEL M. · 1985 to 2014
$6.8M
Mechanisms and applications of recombinational DNA repairU01GM032335 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI COX, MICHAEL M. · 2015 to 2018
$1.7M
NIGMS NIH HHS R01 GM032335NIGMS NIH HHS U01 GM032335
6 · The paper itself

Abstract

The

Indexed as

DNA ReplicationDNA Polymerase IIIEscherichia coliMicroscopy, FluorescenceModels, BiologicalSingle Molecule ImagingDNA Polymerase IIIbiophysicsDNA polymeraseDNA replicationE. colifluorescence microscopymultiprotein complexessingle-moleculestructural biology

Identifiers

PMID28432790
PMCPMC5419744
OpenAlexW2606131944

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.