Evidence map›Paper›PMID 28432616›Full record

ReviewMedical oncology (Northwood, London, England)2017

Prognostic impact of PD-1 and its ligands in renal cell carcinoma.

Franziska Erlmeier, Wilko Weichert, Andres Jan Schrader, Michael Autenrieth, Arndt Hartmann, Sandra Steffens, Philipp Ivanyi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Medical oncology (Northwood, London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Targeting the PD-1/PD-L1 Pathway in Renal Cell Carcinoma.International journal of molecular sciences · 2019
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Franziska ErlmeierInstitute for Pathology and Pathological Anatomy, Technische Universität München, Trogerstraße 18, 81675, Munich, Germany. f.erlmeier@tum.de.
Wilko WeichertInstitute for Pathology and Pathological Anatomy, Technische Universität München, Trogerstraße 18, 81675, Munich, Germany.
Andres Jan SchraderMember of the German Renal Cell Tumor Consortium, Jena, Germany.
Michael AutenriethDepartment of Urology, Technical University of Munich, Klinikum rechts der Isar, Munich, Germany.
Arndt HartmannMember of the German Renal Cell Tumor Consortium, Jena, Germany.
Sandra SteffensMember of the German Renal Cell Tumor Consortium, Jena, Germany.
Philipp IvanyiDepartment of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
Technical University of Munich · DEUniversity Hospital Münster · DEKlinikum rechts der Isar · DEMedizinische Hochschule Hannover · DEUniversitätsklinikum Erlangen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Programmed death-1 receptor (PD-1) and programmed death-1 receptor-ligand (PD-L1) have been suggested to play a role as prognostic markers in clear cell renal cell carcinoma (ccRCC). The association between PD-L1 and prognosis seems to be more robust than for PD-1. Further, preliminary analyses suggest that neither PD-1 nor its ligands play a role as prognostic markers in non-clear cell RCC, while the prognostic role of PD-L2 in ccRCC as well as in non-clear cell RCC remains unclear.

Indexed as

B7-H1 AntigenCarcinoma, Renal CellKidney NeoplasmsProgrammed Cell Death 1 ReceptorHumansPrognosisB7-H1 AntigenCD274 protein, humanPDCD1 protein, humanProgrammed Cell Death 1 ReceptorPD-1PD-L1PD-L2Prognostic impactRenal cell carcinoma

Identifiers

PMID28432616
OpenAlexW2606076978

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.