Evidence map›Paper›PMID 28432550›Full record

ArticleMolecular and cellular biochemistry2017

Estradiol mitigates ischemia reperfusion-induced acute renal failure through NMDA receptor antagonism in rats.

Amrit Pal Singh, Nirmal Singh, Preet Mohinder Singh Bedi

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular and cellular biochemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. N-methyl-D-aspartate receptor inhibition protects against obesity-induced kidney disease.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2026
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  9. Comparison of diabetic nephropathy between male and female eNOSAmerican journal of physiology. Renal physiology · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Amrit Pal SinghDepartment of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, 143005, India.
Nirmal SinghDepartment of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, India.
Preet Mohinder Singh BediDepartment of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, 143005, India. preet.pharma@gndu.ac.in.
Guru Nanak Dev University · INPunjabi University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present study, we investigated possible involvement of N-methyl-D-aspartate receptors (NMDAR) in estradiol mediated protection against ischemia reperfusion (I/R)-induced acute renal failure (ARF) in rats. Bilateral renal ischemia of 40 min followed by reperfusion for 24 h induced ARF in male wistar rats. Quantification of serum creatinine, creatinine clearance (CrCl), blood urea nitrogen (BUN), uric acid, potassium, fractional excretion of sodium (Fe

Indexed as

Acute Kidney InjuryAnimalsBlood Urea NitrogenEstradiolExcitatory Amino Acid AntagonistsKidneyMaleOxidative StressProteinuriaRatsRats, WistarReceptors, N-Methyl-D-AspartateReperfusion InjuryUric AcidEstradiolExcitatory Amino Acid AntagonistsReceptors, N-Methyl-D-AspartateUric AcidEstradiolIschemiaKidneyNMDAOxidative stress

Identifiers

PMID28432550
OpenAlexW2607229254

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.