Evidence map›Paper›PMID 28432514›Full record

ArticleBreast cancer research and treatment2017

Breast cancer treatment costs in younger, privately insured women.

Benjamin T Allaire, Donatus U Ekwueme, Diana Poehler, Cheryll C Thomas, Gery P Guy, Sujha Subramanian, Justin G Trogdon

Abstract read
In one paragraph

Article in Breast cancer research and treatment, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  11. Long-term cost of breast cancer treatment to the United States Medicare Program by stage at diagnosis.The European journal of health economics : HEPAC : health economics in prevention and care · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Benjamin T AllaireRTI International, Research Triangle Park, 3040 East Cornwallis Road, Durham, NC, 27709, USA. ballaire@rti.org.ORCID http://orcid.org/0000-0002-7033-2129
Donatus U EkwuemeCenters for Disease Control and Prevention, Atlanta, Georgia.
Diana PoehlerRTI International, Research Triangle Park, 3040 East Cornwallis Road, Durham, NC, 27709, USA.
Cheryll C ThomasCenters for Disease Control and Prevention, Atlanta, Georgia.
Gery P GuyCenters for Disease Control and Prevention, Atlanta, Georgia.
Sujha SubramanianRTI International, Research Triangle Park, 3040 East Cornwallis Road, Durham, NC, 27709, USA.
Justin G TrogdonUniversity of North Carolina, Chapel Hill, NC, USA.

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

purposeYounger women (under age 45 years) diagnosed with breast cancer often face more aggressive tumors, higher treatment intensity, lower survival rates, and greater financial hardship. The purpose of this study was to estimate breast cancer costs by stage at diagnosis during the first 18 months of treatment for privately insured younger women.

methodsWe analyzed North Carolina cancer registry data linked to claims data from private insurers from 2003 to 2010. Breast cancer patients were split into two cohorts: a younger and older group aged 21-44 and 45-64 years, respectively. We conducted a cohort study and matched women with and without breast cancer using age, ZIP, and Charlson Comorbidity Index. We calculated mean excess costs between breast cancer and non-breast cancer patients at 6, 12, and 18 months.

resultsFor younger women, AJCC 6th edition stage II cancer was the most common at diagnosis (40%), followed by stage I (34%). On the other hand, older women had more stage I (46%) cancer followed by stage II (34%). The excess costs for younger and older women at 12 months were $97,486 (95% confidence interval [CI] $93,631-101,341) and $75,737 (95% CI $73,962-77,512), respectively. Younger breast cancer patients had both a higher prevalence of later-stage disease and higher within-stage costs.

conclusionsThe study reports high costs of treatment for both younger and older women than a non-cancer comparison group; however, the estimated excess cost was significantly higher for younger women. The financial implications of breast cancer treatment costs for younger women need to be explored in future studies.

Indexed as

AdultBreast NeoplasmsCohort StudiesFemaleHealth Care CostsHumansInsurance, HealthMiddle AgedNeoplasm StagingNorth CarolinaPrevalenceYoung AdultBreast cancerCancer stageMedical care costsPrivate insuranceYounger women

Identifiers

PMID28432514
PMCPMC6083444

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.