Evidence map›Paper›PMID 28432444›Full record

ArticleInternational journal of colorectal disease2017

Endoscopic ultrasonography and computed tomography scanning for preoperative staging of colonic cancer.

M L Malmstrøm, I Gögenur, L B Riis, H Hassan, T W Klausen, T Perner, A Săftoiu, P Vilmann

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in International journal of colorectal disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02324023 (Endoscopic Ultrasound Scanning and Contrast Enhancement for Staging and Evaluation of Angiogenesis of Left Sided Colon Cancers), which is not on this map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02324023 nacompletednot on this map

Endoscopic Ultrasound Scanning and Contrast Enhancement for Staging and Evaluation of Angiogenesis of Left Sided Colon Cancers

TypeinterventionalSponsorZealand University HospitalRan2014 to 2016Enrolled35ConditionsColonic NeoplasmsArmsEndoscopic ultrasound
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

M L MalmstrømDepartment of Surgery, Herlev Hospital, University of Copenhagen, Herlev, Denmark. malmstroem@gmail.com.ORCID http://orcid.org/0000-0002-3484-1903
I GögenurDepartment of Surgery, Zealand University Hospital, University of Copenhagen, Køge, Denmark.
L B RiisDepartment of Pathology, Herlev Hospital, University of Copenhagen, Herlev, Denmark.
H HassanDepartment of Surgery, Herlev Hospital, University of Copenhagen, Herlev, Denmark.
T W KlausenDepartment of Hematology, Herlev Hospital, University of Copenhagen, Herlev, Denmark.
T PernerDepartment of Radiology, Zealand University Hospital, University of Copenhagen, Roskilde, Denmark.
A SăftoiuResearch Centre of Gastroenterology and Hepatology, University of Medicine and Pharmacy, Craiova, Romania.
P VilmannDepartment of Surgery, Herlev Hospital, University of Copenhagen, Herlev, Denmark.
University of Copenhagen · DKUniversity of Medicine and Pharmacy of Craiova · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWith an increasing demand for more accurate preoperative staging methods for colon cancer, we aimed to compare preoperative tumour (T)- and nodal (N)-stage in patients with left-sided colon cancer by endoscopic ultrasonography (EUS) and computed tomography (CT) with post-operative histology as gold standard.

methodsA total of 44 patients were prospectively recruited at Herlev and Roskilde University Hospitals during November 2014-January 2016. Thirty-five patients were included in the final analysis and underwent EUS, CT and surgery within 2 weeks. Diagnostic values were evaluated for "low risk" (T1+T2+T3 with ≤5 mm extramural invasion) and "high risk" (T3 with >5 mm of extramural spread + T4) colonic cancer.

resultsSensitivity and specificity in "low risk" colonic cancer evaluated with EUS was 0.90 [0.74;0.98] and 0.75 [0.19;0.99] and with CT 0.96 [0.80;0.99] and 0.25 [<0.01;0.81]. EUS and CT were poor in predicting N0 or N+ disease.

conclusionsThe sensitivity of EUS and CT were good and comparable regarding T-stage evaluation, while EUS had a significantly higher specificity in the evaluation of "low risk" tumours. The results obtained for "high risk" colonic cancer were difficult to evaluate due to small patient numbers. EUS could be considered as a supplement to CT scans in selecting patients for neoadjuvant therapies, or local transmural treatment, in the future.

trial registrationNCT02324023.

Indexed as

EndosonographyTomography, X-Ray ComputedAdenocarcinomaAgedAged, 80 and overColonic NeoplasmsDemographyFemaleHumansMaleMiddle AgedNeoplasm StagingPreoperative CareRisk FactorsColonic cancerEndoscopic ultrasoundImage modalitiesNeoadjuvant therapyStaging

Identifiers

PMID28432444
OpenAlexW2606704730

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.