Evidence map›Paper›PMID 28432351›Full record

ArticleScientific reports2017

Early measurement of IL-10 predicts the outcomes of patients with acute respiratory distress syndrome receiving extracorporeal membrane oxygenation.

Chia-Hsiung Liu, Shuenn-Wen Kuo, Wen-Je Ko, Pi-Ru Tsai, Shu-Wei Wu, Chien-Heng Lai, Chih-Hsien Wang, Yih-Sharng Chen, Pei-Lung Chen, Tze-Tze Liu and 2 more

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Liquid Lung Rest During Extracorporeal Life Support in a Neonatal Porcine Model of Acute Lung Injury.ASAIO journal (American Society for Artificial Internal Organs : 1992) · 2026
    Article
  3. Article
  4. Article
  5. Distinct Blood and Lung Proteins Drive Pulmonary Capillary Leak in Children With Severe Hypoxemic Respiratory Failure.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2026
    Observational
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  19. Article
  20. Acute kidney injury in ECMO patients.Critical care (London, England) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Chia-Hsiung LiuGraduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.
Shuenn-Wen KuoDepartment of Surgery, National Taiwan University Hospital, Taipei, Taiwan.
Wen-Je KoDepartment of Surgery, National Taiwan University Hospital, Taipei, Taiwan.
Pi-Ru TsaiDepartment of Surgery, National Taiwan University Hospital, Taipei, Taiwan.
Shu-Wei WuDepartment of Surgery, National Taiwan University Hospital, Taipei, Taiwan.
Chien-Heng LaiDepartment of Surgery, National Taiwan University Hospital, Taipei, Taiwan.
Chih-Hsien WangDepartment of Surgery, National Taiwan University Hospital, Taipei, Taiwan.
Yih-Sharng ChenDepartment of Surgery, National Taiwan University Hospital, Taipei, Taiwan.
Pei-Lung ChenGraduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.
Tze-Tze LiuGenome Research Center, National Yang-Ming University, Taipei, Taiwan.
Shu-Chien HuangDepartment of Surgery, National Taiwan University Hospital, Taipei, Taiwan. dtsurg99@yahoo.com.tw.
Tzuu-Shuh JouGraduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan. jouts@ntu.edu.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients diagnosed with acute respiratory distress syndrome are generally severely distressed and associated with high morbidity and mortality despite aggressive treatments such as extracorporeal membrane oxygenation (ECMO) support. To identify potential biomarker of predicting value for appropriate use of this intensive care resource, plasma interleukin-10 along with relevant inflammatory cytokines and immune cell populations were examined during the early and subsequent disease courses of 51 critically ill patients who received ECMO support. High interleukin-10 levels at the time of ECMO installation and during the first 6 hours after ECMO support of these patients stand as a promising biomarker associated with grave prognosis. The initial interleukin-10 level is correlated to other conventional risk evaluation scores as a predictive factor for survival, and furthermore, elevated interleukin-10 levels are also related to a delayed recovery of certain immune cell populations such as CD14

Indexed as

AdultAgedCritical IllnessExtracorporeal Membrane OxygenationFemaleHumansInterleukin-10MaleMiddle AgedPrognosisPromoter Regions, GeneticRespiratory Distress SyndromeSeverity of Illness IndexSurvival AnalysisIL10 protein, humanInterleukin-10

Identifiers

PMID28432351
PMCPMC5430643

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.