SynthesisScientific reports2017
Laparoscopic Versus Open Liver Resection for Colorectal Liver Metastases: A Comprehensive Systematic Review and Meta-analysis.
Synthesis in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 31 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Safety and long-term prognosis of simultaneous versus staged resection in synchronous colorectal cancer with liver metastasis: a systematic review and meta-analysis.European journal of medical research · 2022Pooled it
- Minimally invasive versus open hepatectomy for the resection of colorectal liver metastases: a systematic review and meta-analysis.Surgical endoscopy · 2022Pooled it
- Is Single-Incision Laparoscopic Liver Surgery Safe and Efficient for the Treatment of Malignant Hepatic Tumors? A Systematic Review.Journal of gastrointestinal cancer · 2020Pooled it
- Goal-directed fluid therapy during post-resection phase in low central venous pressure assisted laparoscopic hepatectomy: a randomized controlled superiority trial.Journal of anesthesia · 2024Trial
- Toward augmented reality in laparoscopic liver surgery using electromagnetic tracking: a clinical feasibility study.Surgical endoscopy · 2026Article
- Laparoscopic vs. open liver resection for malignancies involving segment 7: short-term outcomes and learning curve analysis using propensity score matching.Surgical endoscopy · 2026Article
- Laparoscopic versus open liver resection in patients aged at least 80 years: retrospective propensity score-matched cohort study.BJS open · 2025Article
- Can liver venous system diameters predict difficulty of laparoscopic liver resection?BMC surgery · 2025Article
- Laparoscopic versus open liver resection for large (≥ 5 cm) hepatocellular carcinoma in elderly patients: a multicenter propensity score-matched study.Updates in surgery · 2025Article
- Learning curve analysis of 100 consecutive robotic liver resections.Surgical endoscopy · 2025Article
- Robotic versus Laparoscopic Liver Resections for Colorectal Metastases: A Systematic Review and Meta-Analysis.Cancers · 2024Review
- Minimal Invasive Versus Open Surgery for Colorectal Liver Metastases: A Multicenter German StuDoQ|Liver Registry-Based Cohort Analysis in Germany.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2023Article
- Review
- Outcomes and Patient Selection in Laparoscopic vs. Open Liver Resection for HCC and Colorectal Cancer Liver Metastasis.Cancers · 2023Review
- Article
- Liver Resection for Primary Hepatic Angiosarcoma: Bicentric Analysis of a Challenging Entity.Journal of clinical medicine · 2022Article
- Laparoscopic Resection of Synchronous Liver Metastasis Involving the Left Hepatic Vein and the Common Trunk Bifurcation: A Strategy of Parenchyma-Sparing Resection with Left Sectionectomy and 4a Subsegmentectomy by Arantius Approach.Healthcare (Basel, Switzerland) · 2022Article
- Effect of the learning curve on survival after laparoscopic liver resection for colorectal metastases.BJS open · 2022Article
- Article
- International multicentre propensity score-matched analysis comparing robotic versus laparoscopic right posterior sectionectomy.The British journal of surgery · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The effects of laparoscopic liver resection (LLR) and open liver resection (OLR) on oncological outcomes for colorectal cancer liver metastases (CCLM) remain inconclusive. Major databases were searched from January 1992 to October 2016. Effects of LLR vs OLR were determined. The primary endpoints were oncological outcomes. In total, 32 eligible non-randomized studies with 4697 patients (LLR: 1809, OLR: 2888) were analyzed. There were higher rates of clear surgical margins (OR: 1.64, 95%CI: 1.32 to 2.05, p < 0.00001) in the LLR group, without significant differences in disease recurrence, 3- or 5-year overall survival(OS) and disease free survival(DFS) between the two approaches. LLR was associated with less intraoperative blood loss (WMD: -147.46 [-195.78 to -99.15] mL, P < 0.00001) and fewer blood transfusions (OR: 0.41 [0.30-0.58], P < 0.00001), but with longer operation time (WMD:14.44 [1.01 to 27.88] min, P < 0.00001) compared to OLR. Less overall morbidity (OR: 0.64 [0.55 to 0.75], p < 0.00001) and shorter postoperative hospital stay (WMD: -2.36 [-3.06 to -1.66] d, p < 0.00001) were observed for patients undergoing LLR, while there was no statistical difference in mortality. LLR appears to be a safe and feasible alternative to OLR in the treatment of CCLM in selected patients.
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