Evidence map›Paper›PMID 28432216›Full record

ArticleDevelopment (Cambridge, England)2017

Embryonic cholecystitis and defective gallbladder contraction in the

Hiroki Higashiyama, Aisa Ozawa, Hiroyuki Sumitomo, Mami Uemura, Ko Fujino, Hitomi Igarashi, Kenya Imaimatsu, Naoki Tsunekawa, Yoshikazu Hirate, Masamichi Kurohmaru and 3 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Development (Cambridge, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Identification of Gallbladder-Specific Distal Regulatory Sequence of Murine Sox17.Genes to cells : devoted to molecular & cellular mechanisms · 2025
    Article
  6. Genetic background and biliary atresia.World journal of pediatric surgery · 2025
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Generation ofRegenerative therapy · 2024
    Review
  12. Biliary Atresia Animal Models: Is the Needle in a Haystack?International journal of molecular sciences · 2022
    Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Hiroki HigashiyamaDepartment of Veterinary Anatomy, The University of Tokyo, Yayoi 1-1-1, Bunkyo-ku, Tokyo 113-8657, Japan.ORCID 0000-0003-1324-8139
Aisa OzawaDepartment of Veterinary Anatomy, The University of Tokyo, Yayoi 1-1-1, Bunkyo-ku, Tokyo 113-8657, Japan.ORCID 0000-0002-0506-5909
Hiroyuki SumitomoDepartment of Veterinary Anatomy, The University of Tokyo, Yayoi 1-1-1, Bunkyo-ku, Tokyo 113-8657, Japan.ORCID 0000-0003-0916-7846
Mami UemuraDepartment of Veterinary Anatomy, The University of Tokyo, Yayoi 1-1-1, Bunkyo-ku, Tokyo 113-8657, Japan.ORCID 0000-0003-0036-3103
Ko FujinoDepartment of Veterinary Anatomy, The University of Tokyo, Yayoi 1-1-1, Bunkyo-ku, Tokyo 113-8657, Japan.
Hitomi IgarashiDepartment of Veterinary Anatomy, The University of Tokyo, Yayoi 1-1-1, Bunkyo-ku, Tokyo 113-8657, Japan.
Kenya ImaimatsuDepartment of Veterinary Anatomy, The University of Tokyo, Yayoi 1-1-1, Bunkyo-ku, Tokyo 113-8657, Japan.
Naoki TsunekawaDepartment of Veterinary Anatomy, The University of Tokyo, Yayoi 1-1-1, Bunkyo-ku, Tokyo 113-8657, Japan.
Yoshikazu HirateCenter for Experimental Animals, Tokyo Medical and Dental University, Yushima 1-5-45, Bunkyo-ku, Tokyo 113-8510, Japan.
Masamichi KurohmaruDepartment of Veterinary Anatomy, The University of Tokyo, Yayoi 1-1-1, Bunkyo-ku, Tokyo 113-8657, Japan.
Yukio SaijohDepartment of Neurobiology and Anatomy, The University of Utah, Salt Lake City, UT 84132-3401, USA.
Masami Kanai-AzumaCenter for Experimental Animals, Tokyo Medical and Dental University, Yushima 1-5-45, Bunkyo-ku, Tokyo 113-8510, Japan.
Yoshiakira KanaiDepartment of Veterinary Anatomy, The University of Tokyo, Yayoi 1-1-1, Bunkyo-ku, Tokyo 113-8657, Japan aykanai@mail.ecc.u-tokyo.ac.jp.ORCID 0000-0003-2116-7806
The University of Tokyo · JPTokyo Medical and Dental University · JPUniversity of Utah · US

Funding

The Roles of Definitive Endoderm in Establishment of Left-Right AsymmetryR01HD066121 · NICHD · UNIVERSITY OF UTAH · PI SAIJOH, YUKIO · 2010 to 2014
$1.5M
NICHD NIH HHS R01 HD066121
6 · The paper itself

Abstract

The gallbladder excretes cytotoxic bile acids into the duodenum through the cystic duct and common bile duct system.

Indexed as

Biliary AtresiaAnimalsCells, CulturedCholecystitisDisease Models, AnimalEmbryo, MammalianFemaleGallbladderHaploinsufficiencyHedgehog ProteinsHMGB ProteinsMaleMiceMice, Inbred C57BLMice, TransgenicMuscle ContractionHedgehog ProteinsHMGB ProteinsShh protein, mouseSox17 protein, mouseSOXF Transcription FactorsBiliary atresiaGallbladderShhSox17

Identifiers

PMID28432216
PMCPMC5450840
OpenAlexW2606597162

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.