Evidence map›Paper›PMID 28432145›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2017

Bacterial Siderophores Hijack Neutrophil Functions.

Piu Saha, Beng San Yeoh, Rodrigo A Olvera, Xia Xiao, Vishal Singh, Deepika Awasthi, Bhagawat C Subramanian, Qiuyan Chen, Madhu Dikshit, Yanming Wang and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 69 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Lipocalin-2 and intestinal diseases.World journal of gastroenterology · 2024
    Review
  11. Article
  12. Article
  13. Circulating Iron in Patients with Sickle Cell Disease Mediates the Release of Neutrophil Extracellular Traps.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2023
    Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. Transcriptomic Analysis ofAntioxidants (Basel, Switzerland) · 2022
    Article
  20. Hemochromatosis drives acute lethal intestinal responses to hyperyersiniabactin-producingProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Piu SahaDepartment of Nutritional Sciences, The Pennsylvania State University, University Park, PA 16802.
Beng San YeohDepartment of Nutritional Sciences, The Pennsylvania State University, University Park, PA 16802.
Rodrigo A OlveraDepartment of Nutritional Sciences, The Pennsylvania State University, University Park, PA 16802.
Xia XiaoDepartment of Nutritional Sciences, The Pennsylvania State University, University Park, PA 16802.
Vishal SinghDepartment of Nutritional Sciences, The Pennsylvania State University, University Park, PA 16802.
Deepika AwasthiPharmacology Division, CSIR-Central Drug Research Institute, Lucknow 226031, India.
Bhagawat C SubramanianLaboratory of Cellular and Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892.
Qiuyan ChenDepartment of Nutritional Sciences, The Pennsylvania State University, University Park, PA 16802.
Madhu DikshitPharmacology Division, CSIR-Central Drug Research Institute, Lucknow 226031, India.
Yanming WangCenter for Eukaryotic Gene Regulation, Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA 16802; and.
Carole A ParentLaboratory of Cellular and Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892.
Matam Vijay-KumarDepartment of Nutritional Sciences, The Pennsylvania State University, University Park, PA 16802; mvk13@psu.edu.
Pennsylvania State University · USCentral Drug Research Institute · INNational Institutes of Health · USNational Cancer Institute · US

Funding

CHEMOTACTIC SIGNALS REGULATING HUMAN NEUTROPHIL AND BREAST METASTATIC MIGRATIONZIABC011216 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI PARENT, CAROLE · 2009 to 2017
$8.6M
Role of Lipocalin 2 Inflammatory Bowel DiseaseR01DK097865 · NIDDK · PENNSYLVANIA STATE UNIVERSITY, THE · PI VIJAY-KUMAR, MATAM · 2013 to 2015
$897k
NIDDK NIH HHS R01 DK097865
6 · The paper itself

Abstract

Neutrophils are the primary immune cells that respond to inflammation and combat microbial transgression. To thrive, the bacteria residing in their mammalian host have to withstand the antibactericidal responses of neutrophils. We report that enterobactin (Ent), a catecholate siderophore expressed by

Indexed as

AnimalsChemotaxisEnterobactinEscherichia coliExtracellular TrapsHumansIronLipocalin-2MiceNeutrophilsPhagocytosisSiderophoresTetradecanoylphorbol AcetateEnterobactinIronLipocalin-2SiderophoresTetradecanoylphorbol Acetate

Identifiers

PMID28432145
PMCPMC5470626
OpenAlexW2619848801

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.