Evidence map›Paper›PMID 28432124›Full record

ArticleThe Journal of biological chemistry2017

Regulation of neurite morphogenesis by interaction between R7 regulator of G protein signaling complexes and G protein subunit Gα

Stephanie L Scherer, Matthew D Cain, Stanley M Kanai, Kevin M Kaltenbronn, Kendall J Blumer

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Synaptic Gα12/13 signaling establishes hippocampal PV inhibitory circuits.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. A familial t(4;8) translocation segregates with epilepsy and migraine with aura.Annals of clinical and translational neurology · 2020
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Stephanie L SchererFrom the Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, Missouri 63110.
Matthew D CainFrom the Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, Missouri 63110.
Stanley M KanaiFrom the Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, Missouri 63110.
Kevin M KaltenbronnFrom the Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, Missouri 63110.
Kendall J BlumerFrom the Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, Missouri 63110 kblumer@wustl.edu.
Washington University in St. Louis · US

Funding

MECHANISM &REGULATION OF RECEPTOR G PROTEIN SIGNALINGR01GM044592 · NIGMS · WASHINGTON UNIVERSITY · PI BLUMER, KENDALL J · 1990 to 2017
$7.5M
RGS PROTEIN FUNCTION AND REGULATIONR01HL075632 · NHLBI · WASHINGTON UNIVERSITY · PI BLUMER, KENDALL J · 2005 to 2013
$4.5M
NHLBI NIH HHS R01 HL075632NIGMS NIH HHS R01 GM044592
6 · The paper itself

Abstract

The R7 regulator of G protein signaling family (R7-RGS) critically regulates nervous system development and function. Mice lacking all R7-RGS subtypes exhibit diverse neurological phenotypes, and humans bearing mutations in the retinal R7-RGS isoform RGS9-1 have vision deficits. Although each R7-RGS subtype forms heterotrimeric complexes with Gβ

Indexed as

Amino Acid SubstitutionAnimalsBrainCarrier ProteinsCell LineGTP-Binding Protein alpha Subunits, G12-G13HumansIntracellular Signaling Peptides and ProteinsMaleMiceMice, TransgenicMutationNerve Tissue ProteinsNeuritesNeuronsPeptide FragmentsCarrier ProteinsGTP-Binding Protein alpha Subunits, G12-G13Intracellular Signaling Peptides and ProteinsNerve Tissue ProteinsPeptide FragmentsR7BP protein, mouseRecombinant Fusion ProteinsRecombinant ProteinsRGS7BP protein, humanRGS7 protein, humanRgs7 protein, mouseRGS ProteinsG proteinheterotrimeric G proteinneurite outgrowthproteomicsregulator of G protein signaling (RGS)

Identifiers

PMID28432124
PMCPMC5473243
OpenAlexW2606354867

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.