Evidence map›Paper›PMID 28431846›Full record

ArticleAmerican journal of infection control2017

Implementation of daily chlorhexidine bathing to reduce colonization by multidrug-resistant organisms in a critical care unit.

Jackson S Musuuza, Ajay K Sethi, Tonya J Roberts, Nasia Safdar

Abstract read
In one paragraph

Article in American journal of infection control, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Influence of antibiotic pressure on multi-drug resistantAntimicrobial resistance and infection control · 2019
    Observational
  6. Is it cost effective to use a 2% chlorhexidine wipes bath to reduce central-line associated blood stream infection? A quasi-experimental study.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jackson S MusuuzaWilliam S. Middleton Memorial Veterans Affairs Hospital, Madison, WI; Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI.
Ajay K SethiDepartment of Population Health Sciences, University of Wisconsin, Madison, WI.
Tonya J RobertsWilliam S. Middleton Memorial Veterans Affairs Hospital, Madison, WI; School of Nursing, University of Wisconsin, Madison, WI.
Nasia SafdarWilliam S. Middleton Memorial Veterans Affairs Hospital, Madison, WI; Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI. Electronic address: ns2@medicine.wisc.edu.

Funding

Implementation of Chlorhexidine Bathing to Reduce Healthcare-Associated Infections-the Icare studyR18HS024039 · AHRQ · UNIVERSITY OF WISCONSIN-MADISON · PI SAFDAR, NASIA · 2015 to 2017
$1.5M
AHRQ HHS R18 HS024039
6 · The paper itself

Abstract

backgroundColonized patients are a reservoir for transmission of multidrug-resistant organisms (MDROs). Not many studies have examined the effectiveness of daily chlorhexidine gluconate (CHG) bathing under routine care conditions. We present a descriptive analysis of the trends of MDRO colonization following implementation of daily CHG bathing under routine clinical conditions in an intensive care unit (ICU).

methodsFrom May 2010-January 2011, we screened patients admitted to a 24-bed ICU for and methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococci (VRE), and fluoroquinolone-resistant gram-negative bacilli (FQRGNB). We calculated and plotted monthly incidence and prevalence of colonization of these MDROs.

resultsPrevalence decreased in the immediate aftermath of daily CHG bathing implementation and generally remained at that level throughout the observation period. We observed low rates of incidence of MDRO colonization with VRE>FQRGNB>MRSA. Monthly prevalence of colonization and incidence for the composite of MRSA, VRE, and/or FQRGNB was 1.9%-27.9% and 0-1.1/100 patient-days, respectively.

conclusionsFollowing the implementation of daily CHG bathing, the incidence of MDROs remained low and constant over time, whereas the prevalence decreased immediately after the implementation.

Indexed as

BathsAdultAgedAged, 80 and overAnti-Infective Agents, LocalChlorhexidineColony Count, MicrobialCritical IllnessDermatologic AgentsDrug Resistance, BacterialFemaleFluoroquinolonesGram-Negative BacteriaHumansIntensive Care UnitsMaleAnti-Infective Agents, LocalChlorhexidinechlorhexidine gluconateDermatologic AgentsFluoroquinolonesAntisepticsBacterial colonizationInfection preventionSustainability of intervention

Identifiers

PMID28431846
PMCPMC6800149

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.