Evidence map›Paper›PMID 28431512›Full record

ArticleEuropean journal of medical research2017

Hemoglobin A1c and risk of left atrial thrombus and spontaneous echo contrast in non-valvular atrial fibrillation patients.

Rong-Ren Kuang, Fang-Zhou Liu, Yun-Peng Li, Wei-Dong Lin, Hua-Sheng Liang, Ai-Hua Chen

Open access · goldAbstract read
In one paragraph

Article in European journal of medical research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Rong-Ren KuangDepartment of Cardiology, Zhujiang Hospital, Southern Medical University, No. 253, Gong Ye Road, Guangzhou, 510282, China.
Fang-Zhou LiuDepartment of Cardiovascular, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Yun-Peng LiDepartment of Cardiology, Zhujiang Hospital, Southern Medical University, No. 253, Gong Ye Road, Guangzhou, 510282, China.
Wei-Dong LinDepartment of Cardiovascular, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Hua-Sheng LiangDepartment of Cardiovascular, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Ai-Hua ChenDepartment of Cardiology, Zhujiang Hospital, Southern Medical University, No. 253, Gong Ye Road, Guangzhou, 510282, China. 501318568@qq.com.
Guangdong General Hospital · CNSouthern Medical University · CNGuangdong Academy of Medical Sciences · CNZhujiang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the relationship between hemoglobin A1c (HbA1c) and risk of left atrial thrombus/spontaneous echo contrast (LAT/SEC) in non-valvular atrial fibrillation (AF) patients.

methodsIn this retrospective study, 1158 consecutive non-valvular AF patients undergoing transesophageal echocardiography prior to radiofrequency catheter ablation or electric cardioversion were enrolled. Baseline characteristics were collected and analyzed.

resultsThere were 87 (7.5%) patients with LAT/SEC. The HbA1c levels in the patients with LAT/SEC were significantly higher than that in patients without LAT/SEC (6.13 ± 0.41 vs. 5.89 ± 0.45 μmol/L, P < 0.001). The optimal cut-off point for HbA1c predicting LAT/SEC was 6.1% determined by receiver-operating characteristic curve. The area under the curve is 0.788 (95% confidence interval: 0.764-0.812). HbA1c ≥6.1% was an independent risk factor for LAT/SEC (odds ratio, 1.74; 95% confidence interval, 1.01-2.98; P = 0.045).

conclusionsElevated HbA1c indicated a significantly increased risk for LAT/SEC in non-valvular AF patients. HbA1c might have significance in predicting the risk for prothrombotic state in non-valvular AF patients.

Indexed as

AgedAtrial FibrillationCatheter AblationContrast MediaEchocardiography, TransesophagealFemaleGlycated HemoglobinHeart AtriaHumansMaleMiddle AgedRisk FactorsThrombosisContrast MediaGlycated Hemoglobinhemoglobin A1c protein, humanAtrial fibrillationHemoglobin A1cLeft atrial thrombusProthrombotic stateSpontaneous echo contrast

Identifiers

PMID28431512
PMCPMC5401472
OpenAlexW2607397775

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.