ArticleRespiratory research2017
Outcomes after early and delayed rehabilitation for exacerbation of chronic obstructive pulmonary disease: a nationwide retrospective cohort study in Japan.
Article in Respiratory research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Predictors of Readmission, for Patients with Chronic Obstructive Pulmonary Disease (COPD) - A Systematic Review.International journal of chronic obstructive pulmonary disease · 2023Pooled it
- Trial
- Benefits of different intensities of pulmonary rehabilitation for patients with moderate-to-severe COPD according to the GOLD stage: a prospective, multicenter, single-blinded, randomized, controlled trial.International journal of chronic obstructive pulmonary disease · 2019Trial
- Mortality trends and disparities in older U.S. adults with atrial fibrillation and COPD: a 1999-2020 CDC WONDER analysis with forecast to 2030.Frontiers in cardiovascular medicine · 2026Article
- Trends and determinants of acute tocolysis implementation in Japan, 2012-2023: An 11-year nationwide retrospective cohort study.PloS one · 2026Article
- Assistive products for long-term care among older people with chronic obstructive pulmonary disease in Japan: a retrospective cohort study.BMC geriatrics · 2025Article
- Hysterectomy for postpartum hemorrhage in Japan: Diagnostic code validation and nationwide descriptive analysis.The journal of obstetrics and gynaecology research · 2025Article
- Development and validation of a distributed representation model of Japanese high-dimensional administrative claims data for clinical epidemiology studies.BMC medical research methodology · 2025Article
- Association between the Timing of Urinary Antigen Testing and Outcomes in Legionella Pneumonia Patients: A Nationwide Database Study.Internal medicine (Tokyo, Japan) · 2024Article
- Noninvasive Positive Airway Pressure Management for Post-extubation Support in Preterm Infants: Observational Cohort Study with Overlap Weighting Analysis.Annals of clinical epidemiology · 2024Article
- Estimating the Health and Economic Impact of Improved Management in Prevalent Chronic Obstructive Pulmonary Disease Populations in England, Germany, Canada, and Japan: A Modelling Study.International journal of chronic obstructive pulmonary disease · 2023Article
- Development of Deep Learning Models for Predicting In-Hospital Mortality Using an Administrative Claims Database: Retrospective Cohort Study.JMIR medical informatics · 2022Article
- Placental abruption in each hypertensive disorders of pregnancy phenotype: a retrospective cohort study using a national inpatient database in Japan.Hypertension research : official journal of the Japanese Society of Hypertension · 2021Article
- Inappropriate use of ritodrine hydrochloride for threatened preterm birth in Japan: a retrospective cohort study using a national inpatient database.BMC pregnancy and childbirth · 2019Article
- Antenatal corticosteroid administration in women undergoing tocolytic treatment who delivered before 34 weeks of gestation: a retrospective cohort study using a national inpatient database.BMC pregnancy and childbirth · 2019Article
- Relevance of nutritional support and early rehabilitation in hospitalized patients with COPD.Journal of thoracic disease · 2018Review
- Validity of diagnoses, procedures, and birth records in a Japanese administrative claims database for pediatric patients.Pediatrics international : official journal of the Japan Pediatric SocietyArticle
- Differences in plasma amino acid levels in patients with and without bacterial infection during the early stage of acute exacerbation of COPD.International journal of chronic obstructive pulmonary diseaseArticle
- The effect of incentive spirometry with early pulmonary rehabilitation on hospital stay of patients with chronic obstructive pulmonary disease exacerbation.Annals of thoracic medicineArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe effectiveness of early pulmonary rehabilitation (PR) for exacerbation of chronic obstructive pulmonary disease (COPD) remains controversial. The present study aimed to compare the outcomes between early and delayed PR for exacerbation of COPD, using a national inpatient database.
methodsUsing the Japanese Diagnosis Procedure Combination database, we examined patients who were transported to hospital for exacerbation of COPD, received PR during hospitalisation, and were discharged to their home. The patients were divided into those who received early PR (defined as PR starting within 48 h of admission) and those who received delayed PR. The outcomes included 90-day readmission, length of stay (LOS), and activities of daily living (Barthel index ≥15) at discharge. Multiple imputation was used for missing data. To assess the associations between early PR and the outcomes, we used risk-adjusted treatment effects and instrumental variable methods.
resultsWe identified 12,572 eligible patients, including 8459 patients with delayed PR and 4113 with early PR. In the risk-adjusted treatment effect models, the early PR group had lower proportion of 90-day readmission (risk difference, -3.4%; 95% CI, -5.7% to -1.5%) and shorter LOS (-9.8 days; 95% CI, -10.8 days to -8.7 days) than the delayed PR group. There was no significant difference in activities of daily living at discharge between the two groups. The instrumental variable analyses showed similar results.
conclusionsIn this national database study, early PR was associated with reduced 90-day readmission and shortened LOS in patients with exacerbation of COPD.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.