ArticleDNA research : an international journal for rapid publication of reports on genes and genomes2017
Somatic transposition and meiotically driven elimination of an active helitron family in Pleurotus ostreatus.
Article in DNA research : an international journal for rapid publication of reports on genes and genomes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 7 citations in OpenAlex.
- An active Helitron transposon family in wheat.Nature plants · 2026Article
- Antifungal Activity of Chitosan/Poly(Ethylene Oxide) Blend Electrospun Polymeric Fiber Mat Doped with Metallic Silver Nanoparticles.Polymers · 2023Article
- Stage-specific transposon activity in the life cycle of the fairy-ring mushroomProceedings of the National Academy of Sciences of the United States of America · 2022Article
- Strain Degeneration inJournal of fungi (Basel, Switzerland) · 2021Article
- Comparative Genomics Supports Sex and Meiosis in Diverse Amoebozoa.Genome biology and evolution · 2018Article
- Transposon-associated epigenetic silencing during Pleurotus ostreatus life cycle.DNA research : an international journal for rapid publication of reports on genes and genomes · 2018Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Helitrons constitute a superfamily of DNA transposons that were discovered in silico and are widespread in most eukaryotic genomes. They are postulated to mobilize through a "rolling-circle" mechanism, but the experimental evidence of their transposition has been described only recently. Here, we present the inheritance patterns of HELPO1 and HELPO2 helitron families in meiotically derived progeny of the basidiomycete Pleurotus ostreatus. We found distorted segregation patterns of HELPO2 helitrons that led to a strong under-representation of these elements in the progeny. Further investigation of HELPO2 flanking sites showed that gene conversion may contribute to the elimination of such repetitive elements in meiosis, favouring the presence of HELPO2 vacant loci. In addition, the analysis of HELPO2 content in a reconstructed pedigree of subclones maintained under different culture conditions revealed an event of helitron somatic transposition. Additional analyses of genome and transcriptome data indicated that P. ostreatus carries active RNAi machinery that could be involved in the control of transposable element proliferation. Our results provide the first evidence of helitron mobilization in the fungal kingdom and highlight the interaction between genome defence mechanisms and invasive DNA.
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Registered trials
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