Evidence map›Paper›PMID 28430997›Full record

ReviewThe Journal of infectious diseases2017

Global Impact of Rotavirus Vaccination on Childhood Hospitalizations and Mortality From Diarrhea.

Eleanor Burnett, Christine L Jonesteller, Jacqueline E Tate, Catherine Yen, Umesh D Parashar

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The Journal of infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 130 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
130citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

130 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  13. A phase I trial of WRSS1, aHuman vaccines & immunotherapeutics · 2019
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70 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Eleanor BurnettCDC Foundation.
Christine L JonestellerCDC Foundation.
Jacqueline E TateCenters for Disease Control and Prevention, Atlanta, Georgia.
Catherine YenCenters for Disease Control and Prevention, Atlanta, Georgia.
Umesh D ParasharCenters for Disease Control and Prevention, Atlanta, Georgia.

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

In 2006, 2 rotavirus vaccines were licensed. We summarize the impact of rotavirus vaccination on hospitalizations and deaths from rotavirus and all-cause acute gastroenteritis (AGE) during the first 10 years since vaccine licensure, including recent evidence from countries with high child mortality. We used standardized guidelines (PRISMA) to identify observational evaluations of rotavirus vaccine impact among children <5 years of age that presented at least 12 months of pre- and post-vaccine introduction surveillance data. We identified 57 articles from 27 countries. Among children <5 years of age, the median percentage reduction in AGE hospitalizations was 38% overall and 41%, 30%, and 46% in countries with low, medium, and high child mortality, respectively. Hospitalizations and emergency department visits due to rotavirus AGE were reduced by a median of 67% overall and 71%, 59%, and 60% in countries with low, medium, and high child mortality, respectively. Implementation of rotavirus vaccines has substantially decreased hospitalizations from rotavirus and all-cause AGE.

Indexed as

VaccinationChild, PreschoolDiarrheaEmergency Service, HospitalGastroenteritisHospitalizationHumansInfantInfant, NewbornRotavirusRotavirus InfectionsRotavirus VaccinesRotavirus VaccinesdiarrhearotavirusRotavirus vaccine

Identifiers

PMID28430997
PMCPMC5543929

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.