ArticleAmerican journal of epidemiology2017
Effects of Antiretroviral Therapy and Depressive Symptoms on All-Cause Mortality Among HIV-Infected Women.
Article in American journal of epidemiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 5 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- The Characteristics and HIV-Related Outcomes of People Living with Co-occurring HIV and Mental Health Conditions in the United States: A Systematic Review of Literature from 2016 to 2021.AIDS and behavior · 2024Pooled it
- Systematic review and meta-analysis on the effect of depression on ART adherence among women living with HIV.PloS one · 2024Pooled it
- Mental health interventions for persons living with HIV in low- and middle-income countries: a systematic review.Journal of the International AIDS Society · 2021Pooled it
- Noncommunicable diseases among HIV-infected persons in low-income and middle-income countries: a systematic review and meta-analysis.AIDS (London, England) · 2018Pooled it
- Living With Chronic HIV Disease in the Antiretroviral Era: The Impact of Neurocognitive Impairment on Everyday Life Functions.Topics in antiviral medicinePooled it
- The kynurenine pathway in relation to depression and anhedonia symptom severity among women with HIV.Brain, behavior, & immunity - health · 2026Article
- Understanding depression and the PHQ-9 items among people living with HIV: A multiple methods qualitative study in Yaoundé, Cameroon.SSM. Mental health · 2024Article
- Lessons Learned from a Community-led, Pilot Teletherapy Group for Older Women Living with Depression and HIV.AIDS and behavior · 2024Article
- Heavy Alcohol Use and HIV Outcomes: The Moderating Role of Pain.AIDS and behavior · 2024Article
- Effect of a brief psychological intervention for common mental disorders on HIV viral suppression: A non-randomised controlled study of the Friendship Bench in Zimbabwe.PLOS global public health · 2024Article
- Correlates of Depression in ART Adherence among Youths in Lilongwe, Malawi.Tropical medicine and infectious disease · 2023Article
- The comorbidity of depression and neurocognitive disorder in persons with HIV infection: call for investigation and treatment.Frontiers in cellular neuroscience · 2023Article
- Loneliness as a mediation from social support leading to a decrease of health-related quality of life among PLWHIV.Frontiers in public health · 2022Article
- Low Neuroactive Steroids Identifies a Biological Subtype of Depression in Adults with Human Immunodeficiency Virus on Suppressive Antiretroviral Therapy.The Journal of infectious diseases · 2021Article
- Natural Language Processing of Clinical Notes to Identify Mental Illness and Substance Use Among People Living with HIV: Retrospective Cohort Study.JMIR medical informatics · 2021Article
- Associations between Antiretroviral Drugs on Depressive Symptomatology in Homogenous Subgroups of Women with HIV.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2021Article
- HIV Infection and Related Mental Disorders.Brain sciences · 2021Review
- Depression, antiretroviral therapy initiation, and HIV viral suppression among people who inject drugs in Vietnam.Journal of affective disorders · 2021Article
- Feasibility of Four Interventions to Improve Treatment Adherence in Migrants Living with HIV in The Netherlands.Diagnostics (Basel, Switzerland) · 2020Article
- Psychological distress in women and men living with HIV in Spain: a cross-sectional telephone survey.Evidence-based mental health · 2020Article
Corrections and comments
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Authors and funding
15 authors.
Funding
Abstract
Depression affects up to 30% of human immunodeficiency virus (HIV)-infected individuals. We estimated joint effects of antiretroviral therapy (ART) initiation and depressive symptoms on time to death using a joint marginal structural model and data from a cohort of HIV-infected women from the Women's Interagency HIV Study (conducted in the United States) from 1998-2011. Among 848 women contributing 6,721 years of follow-up, 194 participants died during follow-up, resulting in a crude mortality rate of 2.9 per 100 women-years. Cumulative mortality curves indicated greatest mortality for women who reported depressive symptoms and had not initiated ART. The hazard ratio for depressive symptoms was 3.38 (95% confidence interval (CI): 2.15, 5.33) and for ART was 0.47 (95% CI: 0.31, 0.70). Using a reference category of women without depressive symptoms who had initiated ART, the hazard ratio for women with depressive symptoms who had initiated ART was 3.60 (95% CI: 2.02, 6.43). For women without depressive symptoms who had not started ART, the hazard ratio was 2.36 (95% CI: 1.16, 4.81). Among women reporting depressive symptoms who had not started ART, the hazard ratio was 7.47 (95% CI: 3.91, 14.3). We found a protective effect of ART initiation on mortality, as well as a harmful effect of depressive symptoms, in a cohort of HIV-infected women.
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