Evidence map›Paper›PMID 28430550›Full record

ArticleJournal of athletic training2017

Round Table on Malignant Hyperthermia in Physically Active Populations: Meeting Proceedings.

Yuri Hosokawa, Douglas J Casa, Henry Rosenberg, John F Capacchione, Emmanuel Sagui, Sheila Riazi, Luke N Belval, Patricia A Deuster, John F Jardine, Stavros A Kavouras and 10 more

Abstract readConsensus Statement
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of athletic training, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Is Heat Intolerance State or Trait?Sports medicine (Auckland, N.Z.) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Yuri HosokawaDepartment of Kinesiology, Korey Stringer Institute, University of Connecticut, Storrs.
Douglas J CasaDepartment of Kinesiology, Korey Stringer Institute, University of Connecticut, Storrs.
Henry RosenbergSaint Barnabas Medical Center, Livingston, NJ.
John F CapacchioneUniformed Services University of the Health Sciences, Bethesda, MD.
Emmanuel SaguiFrench Military Hospital Laveran, Marseille.
Sheila Riazi
Luke N BelvalDepartment of Kinesiology, Korey Stringer Institute, University of Connecticut, Storrs.
Patricia A DeusterUniformed Services University of the Health Sciences, Bethesda, MD.
John F JardineDepartment of Kinesiology, Korey Stringer Institute, University of Connecticut, Storrs.
Stavros A KavourasDepartment of Health, Human Performance, and Recreation, University of Arkansas, Fayetteville.
Elaine C LeeDepartment of Kinesiology, Korey Stringer Institute, University of Connecticut, Storrs.
Kevin C MillerDepartment of Rehabilitation and Medical Sciences, Central Michigan University, Mount Pleasant.
Sheila M MuldoonUniformed Services University of the Health Sciences, Bethesda, MD.
Francis G O'ConnorUniformed Services University of the Health Sciences, Bethesda, MD.
Scott R SailorDepartment of Kinesiology, California State University, Fresno.
Nyamkhishig SambuughinUniformed Services University of the Health Sciences, Bethesda, MD.
Rebecca L StearnsDepartment of Kinesiology, Korey Stringer Institute, University of Connecticut, Storrs.
William M AdamsDepartment of Kinesiology, Korey Stringer Institute, University of Connecticut, Storrs.
Robert A HugginsDepartment of Kinesiology, Korey Stringer Institute, University of Connecticut, Storrs.
Lesley W VandermarkDepartment of Health, Human Performance, and Recreation, University of Arkansas, Fayetteville.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextRecent case reports on malignant hyperthermia (MH)-like syndrome in physically active populations indicate potential associations among MH, exertional heat stroke (EHS), and exertional rhabdomyolysis (ER). However, an expert consensus for clinicians working with these populations is lacking.

objectiveTo provide current expert consensus on the (1) definition of MH; (2) history, etiology, and pathophysiology of MH; (3) epidemiology of MH; (4) association of MH with EHS and ER; (5) identification of an MH-like syndrome; (6) recommendations for acute management of an MH-like syndrome; (7) special considerations for physically active populations; and (8) future directions for research.

settingAn interassociation task force was formed by experts in athletic training, exercise science, anesthesiology, and emergency medicine. The "Round Table on Malignant Hyperthermia in Physically Active Populations" was convened at the University of Connecticut, Storrs, September 17-18, 2015.

conclusionsClinicians should consider an MH-like syndrome when a diagnosis of EHS or ER cannot be fully explained by clinical signs and symptoms presented by a patient or when recurrent episodes of EHS or ER (or both) are unexplained. Further research is required to elucidate the genetic and pathophysiological links among MH, EHS, and ER.

Indexed as

ConsensusDiagnosis, DifferentialExerciseHeat StrokeHumansMalignant HyperthermiaRecurrenceRhabdomyolysisSyndromeexertional heat strokeexertional rhabdomyolysisryanodine receptor 1

Identifiers

PMID28430550
PMCPMC5402536

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.