Evidence map›Paper›PMID 28430181›Full record

ArticleEye (London, England)2017

Supervised learning and dimension reduction techniques for quantification of retinal fluid in optical coherence tomography images.

A Breger, M Ehler, H Bogunovic, S M Waldstein, A-M Philip, U Schmidt-Erfurth, B S Gerendas

Abstract read
In one paragraph

Article in Eye (London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
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  8. [Artificial intelligence in management of macular edema : Opportunities and challenges].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

A BregerDepartment of Mathematics, University of Vienna, Vienna, Austria.
M EhlerDepartment of Mathematics, University of Vienna, Vienna, Austria.
H BogunovicVienna Reading Center and Christian Doppler Laboratory for Ophthalmic Image Analysis, Department of Ophthalmology, Medical University of Vienna, Vienna, Austria.
S M WaldsteinVienna Reading Center and Christian Doppler Laboratory for Ophthalmic Image Analysis, Department of Ophthalmology, Medical University of Vienna, Vienna, Austria.
A-M PhilipVienna Reading Center and Christian Doppler Laboratory for Ophthalmic Image Analysis, Department of Ophthalmology, Medical University of Vienna, Vienna, Austria.
U Schmidt-ErfurthVienna Reading Center and Christian Doppler Laboratory for Ophthalmic Image Analysis, Department of Ophthalmology, Medical University of Vienna, Vienna, Austria.
B S GerendasVienna Reading Center and Christian Doppler Laboratory for Ophthalmic Image Analysis, Department of Ophthalmology, Medical University of Vienna, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PurposeThe purpose of the present study is to develop fast automated quantification of retinal fluid in optical coherence tomography (OCT) image sets.MethodsWe developed an image analysis pipeline tailored towards OCT images that consists of five steps for binary retinal fluid segmentation. The method is based on feature extraction, pre-segmention, dimension reduction procedures, and supervised learning tools.ResultsFluid identification using our pipeline was tested on two separate patient groups: one associated to neovascular age-related macular degeneration, the other showing diabetic macular edema. For training and evaluation purposes, retinal fluid was annotated manually in each cross-section by human expert graders of the Vienna Reading Center. Compared with the manual annotations, our pipeline yields good quantification, visually and in numbers.ConclusionsBy demonstrating good automated retinal fluid quantification, our pipeline appears useful to expert graders within their current grading processes. Owing to dimension reduction, the actual learning part is fast and requires only few training samples. Hence, it is well-suited for integration into actual manufacturer's devices, further improving segmentation by its use in daily clinical life.

Indexed as

Exudates and TransudatesSupervised Machine LearningDiabetic RetinopathyHumansImage Interpretation, Computer-AssistedMacular DegenerationMacular EdemaRetinaRetinal NeovascularizationTomography, Optical Coherence

Identifiers

PMID28430181
PMCPMC5584504

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.