Evidence map›Paper›PMID 28430144›Full record

ArticleInternational journal of molecular sciences2017

A Systems Biology Approach Using Transcriptomic Data Reveals Genes and Pathways in Porcine Skeletal Muscle Affected by Dietary Lysine.

Taiji Wang, Jean M Feugang, Mark A Crenshaw, Naresh Regmi, John R Blanton, Shengfa F Liao

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

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  11. Lipid metabolism and mJournal of animal science and biotechnology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Taiji WangDepartment of Animal and Dairy Sciences, Mississippi State University, Starkville, MS 39762, USA. wangtaiji@hotmail.com.
Jean M FeugangDepartment of Animal and Dairy Sciences, Mississippi State University, Starkville, MS 39762, USA. jn181@msstate.edu.
Mark A CrenshawDepartment of Animal and Dairy Sciences, Mississippi State University, Starkville, MS 39762, USA. mac4@msstate.edu.
Naresh RegmiDepartment of Animal and Dairy Sciences, Mississippi State University, Starkville, MS 39762, USA. regminar@msu.edu.
John R BlantonDepartment of Animal and Dairy Sciences, Mississippi State University, Starkville, MS 39762, USA. jblanton@ads.msstate.edu.
Shengfa F LiaoDepartment of Animal and Dairy Sciences, Mississippi State University, Starkville, MS 39762, USA. s.liao@msstate.edu.
Mississippi State University · US

Funding

Training and Mentoring Core P20GM103476 · NIGMS · UNIVERSITY OF SOUTHERN MISSISSIPPI · PI MICHAEL R GARRETT · 2012 to 2026
$60.2M
The role of leptin in autoimmune-associated hypertensionP20GM104357 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI TAYLOR, ERIN BASSFORD · 2013 to 2022
$23.4M
Center for Psychiatric NeuroscienceP30GM103328 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI STOCKMEIER, CRAIG ALLEN · 2013 to 2017
$5.5M
NIGMS NIH HHS P20 GM103476NIGMS NIH HHS P20 GM104357NIGMS NIH HHS P30 GM103328
6 · The paper itself

Abstract

Nine crossbred finishing barrows (body weight 94.4 ± 6.7 kg) randomly assigned to three dietary treatments were used to investigate the effects of dietary lysine on muscle growth related metabolic and signaling pathways. Muscle samples were collected from the longissimus dorsi of individual pigs after feeding the lysine-deficient (4.30 g/kg), lysine-adequate (7.10 g/kg), or lysine-excess (9.80 g/kg) diet for five weeks, and the total RNA was extracted afterwards. Affymetrix Porcine Gene 1.0 ST Array was used to quantify the expression levels of 19,211 genes. Statistical ANOVA analysis of the microarray data showed that 674 transcripts were differentially expressed (at

Indexed as

AnimalsCluster AnalysisDatabases, GeneticDietary SupplementsDose-Response Relationship, DrugDown-RegulationGene Expression ProfilingHSP110 Heat-Shock ProteinsHSP40 Heat-Shock ProteinsHSP90 Heat-Shock ProteinsLipid MetabolismLysineMalate DehydrogenaseMuscle, SkeletalOligonucleotide Array Sequence AnalysisReal-Time Polymerase Chain ReactionHSP110 Heat-Shock ProteinsHSP40 Heat-Shock ProteinsHSP90 Heat-Shock ProteinsLysineMalate Dehydrogenasemalate dehydrogenase (decarboxylating)RNAUbiquitin-Conjugating Enzymesgene expressionlysinemicroarraypigskeletal muscletranscriptome

Identifiers

PMID28430144
PMCPMC5412465
OpenAlexW2609327387

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.