Evidence map›Paper›PMID 28430133›Full record

ReviewDiagnostics (Basel, Switzerland)2017

Nuclear Molecular Imaging Strategies in Immune Checkpoint Inhibitor Therapy.

Kasper F Guldbrandsen, Helle W Hendel, Seppo W Langer, Barbara M Fischer

Open access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. The value ofEuropean journal of nuclear medicine and molecular imaging · 2021
    Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Longitudinal studies of theCancer immunology, immunotherapy : CII · 2018
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Kasper F GuldbrandsenDepartment of Pulmonary and Infectious Diseases, Nordsjællands Hospital Hillerød, 3400 Hillerød, Denmark. kasper.foged.guldbrandsen.01@regionh.dk.
Helle W HendelDepartment of Clinical Physiology and Nuclear Medicine, Herlev and Gentofte Hospital, 2750 Herlev, Denmark. helle.westergren.hendel@regionh.dk.
Seppo W LangerDepartment of Oncology 5073, Rigshospitalet, 2100 Copenhagen, Denmark. seppo.langer@regionh.dk.
Barbara M FischerDepartment of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, 2100 Copenhagen, Denmark. barbara.malene.fischer@regionh.dk.
Rigshospitalet · DKGentofte Hospital · DKNordsjællands Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune checkpoint inhibitor therapy (ICT) is a new treatment strategy developed for the treatment of cancer. ICT inhibits pathways known to downregulate the innate immune response to cancer cells. These drugs have been shown to be effective in the treatment of a variety of cancers, including metastatic melanoma and lung cancer. Challenges in response evaluation of patients in ICT have risen as immune related side effects and immune cell infiltration may be confused with progressive disease. Furthermore, the timing of the evaluation scan may be challenged by relatively slow responses. To overcome this, new response criteria for evaluating these patients with morphologic imaging have been proposed. The aim of this paper is to review and discuss the current evidence for the use of molecular imaging, e.g., PET/CT (Positron Emission Tomography/Computer Tomography) with

Indexed as

immune checkpoint inhibitor therapyPET/CTradiotracerresponse evaluation/treatment monitoring

Identifiers

PMID28430133
PMCPMC5489943
OpenAlexW2606932109

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.