Evidence map›Paper›PMID 28429581›Full record

ArticlePediatric diabetes2018

Nighttime is the worst time: Parental fear of hypoglycemia in young children with type 1 diabetes.

Michelle A Van Name, Marisa E Hilliard, Claire T Boyle, Kellee M Miller, Daniel J DeSalvo, Barbara J Anderson, Lori M Laffel, Stephanie E Woerner, Linda A DiMeglio, William V Tamborlane

Abstract readMulticenter Study
In one paragraph

Article in Pediatric diabetes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed, 2 pooled it
9.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 2 syntheses or guidelines pooled it, 139 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Fear of hypoglycaemia and parent sleep disturbance in families of young children with type 1 diabetes.Diabetic medicine : a journal of the British Diabetic Association · 2026
    Article
  12. Fear of Nighttime Hypoglycemia: Perspectives of Diabetes Providers and Caregivers.Journal of clinical psychology in medical settings · 2026
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Observational
  19. Article
  20. Article

19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Michelle A Van NameYale School of Medicine, New Haven, Connecticut.ORCID 0000-0001-7672-4230
Marisa E HilliardBaylor College of Medicine and Texas Children's Hospital, Houston, Texas.
Claire T BoyleJaeb Center for Health Research, Tampa, Florida.ORCID 0000-0002-6645-2726
Kellee M MillerJaeb Center for Health Research, Tampa, Florida.
Daniel J DeSalvoBaylor College of Medicine and Texas Children's Hospital, Houston, Texas.
Barbara J AndersonBaylor College of Medicine and Texas Children's Hospital, Houston, Texas.
Lori M LaffelJoslin Diabetes Center, Boston, Massachusetts.ORCID 0000-0002-9675-3001
Stephanie E WoernerIndiana University School of Medicine, Indianapolis, Indiana.
Linda A DiMeglioIndiana University School of Medicine, Indianapolis, Indiana.
William V TamborlaneYale School of Medicine, New Haven, Connecticut.
Baylor College of Medicine · USIndiana University School of MedicineJaeb Center for Health Research · USYale University · USJoslin Diabetes Center · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
SPECIAL ASSAY COREP30DK036836 · NIDDK · JOSLIN DIABETES CENTER · PI ROHIT N. KULKARNI · 1986 to 2026
$50.5M
Career Development Programs in Diabetes Research for Pediatrics EndocrinologistsK12DK094714 · NIDDK · YALE UNIVERSITY · PI TAMBORLANE, WILLIAM V · 2011 to 2020
$4.3M
Mentoring Behavioral Scientists for Career Development in Pediatric T1D ResearchK12DK097696 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI ANDERSON, BARBARA JANE · 2012 to 2016
$1.8M
NCATS NIH HHS UL1 TR001863NIDDK NIH HHS K12 DK094714NIDDK NIH HHS K12 DK097696NIDDK NIH HHS P30 DK036836
6 · The paper itself

Abstract

backgroundFear of hypoglycemia is common in parents of young children with type 1 diabetes (T1D), but little is known about the specific fears that parents most often experience. Hypoglycemia fear has been associated with poorer glycemic control in older children, though not yet studied in a large cohort of very young children. MATERIALS AND

methodsParents of 549 children <7 years (mean 5.2 ± 1.2 years [19% <3 years]) with a mean diabetes duration of 2.4 ± 1.0 years (range 1-6 years) and mean HbA1c 8.2% ± 1.1% (66 ± 12 mmol/mol) registered in the T1D Exchange completed the worry scale of the Hypoglycemia Fear Survey modified for parents (HFS-P).

resultsMean parental fear of hypoglycemia worry score was 36.1 ± 23.1 (possible range 0-100), with most frequent worries related to the child having a low while asleep and the child not recognizing a low. The mean worry score was not associated with the child's age, glycemic control, or recent severe hypoglycemic event. Parental worries about lows while sleeping were significantly higher in pump users than non-users (61% vs. 45%; P < .001), and tended to be higher in CGM users than non-users (62% vs 51%; P = .02).

conclusionsThe greatest worries of parents of young children with T1D were related to hypoglycemia during sleep and other times/circumstances during which it would be difficult to detect hypoglycemia. Using advanced diabetes technologies may be an effort to temper fears about hypoglycemia during sleep, though the directionality of this relationship is undetermined. Additional studies can clarify this association and leverage use of diabetes technologies to improve glycemic control.

Indexed as

Diabetes Mellitus, Type 1FearRegistriesAdultChildChild, PreschoolCircadian RhythmFemaleHumansHypoglycemiaHypoglycemic AgentsInsulinMaleParentsHypoglycemic AgentsInsulinfear of hypoglycemiaT1D Exchange clinic registrytype 1 diabetesyoung children

Identifiers

PMID28429581
PMCPMC5650950
OpenAlexW2606209860

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.