ArticleHuman brain mapping2017
Altered eigenvector centrality is related to local resting-state network functional connectivity in patients with longstanding type 1 diabetes mellitus.
Article in Human brain mapping, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 43 citations in OpenAlex.
- Disrupted metabolic connectivity in dopaminergic and cholinergic networks at different stages of dementia fromScientific reports · 2021Trial
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- Brain network alterations in autoimmune diseases: Current status and future prospects.iScience · 2026Review
- Enhanced sensorimotor cortex responsiveness to nonplegic hand stimulation and motor network assembly during recovery after spinal cord injury in primates.Scientific reports · 2026Article
- Social Disconnection in the Brain: Loneliness and Age across Networks using Graph Theory.bioRxiv : the preprint server for biology · 2026Article
- Intestinal short-chain fatty acid turnover is not associated with resting state functional connectivity in mesolimbic dopaminergic network in healthy adults.Neuroimage. Reports · 2025Article
- Association between cerebral lesions and the severity of diabetic cardiovascular disease, retinopathy, and nephropathy-new lessons to learn from neuroimaging.Journal of endocrinological investigation · 2025Review
- Neuroeconomically dissociable forms of mental accounting are altered in a mouse model of diabetes.Communications biology · 2025Article
- Characterization and Classification of ADHD Subtypes: An Approach Based on the Nodal Distribution of Eigenvector Centrality and Classification Tree Model.Child psychiatry and human development · 2024Article
- Well-being is associated with cortical thickness network topology of human brain.Behavioral and brain functions : BBF · 2023Article
- Immune-Related Protein Interaction Network in Severe COVID-19 Patients toward the Identification of Key Proteins and Drug Repurposing.Biomolecules · 2022Article
- A survey of brain network analysis by electroencephalographic signals.Cognitive neurodynamics · 2022Article
- State and Trait Anxiety Share Common Network Topological Mechanisms of Human Brain.Frontiers in neuroinformatics · 2022Article
- Aberrant Interhemispheric Functional Connectivity in Diabetic Retinopathy Patients.Frontiers in neuroscience · 2021Article
- Integrative Models of Brain Structure and Dynamics: Concepts, Challenges, and Methods.Frontiers in neuroscience · 2021Review
- Dynamic Changes of Amplitude of Low-Frequency Fluctuations in Patients With Diabetic Retinopathy.Frontiers in neurology · 2021Article
- Large-Scale Neuronal Network Dysfunction in Diabetic Retinopathy.Neural plasticity · 2020Article
- Intrinsic Connectivity Changes Mediate the Beneficial Effect of Cardiovascular Exercise on Sustained Visual Attention.Cerebral cortex communications · 2020Article
- A concise and persistent feature to study brain resting-state network dynamics: Findings from the Alzheimer's Disease Neuroimaging Initiative.Human brain mapping · 2019Article
- Eigenvector Centrality Dynamics From Resting-State fMRI: Gender and Age Differences in Healthy Subjects.Frontiers in neuroscience · 2019Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 3 countries.
Funding
Abstract
introductionLongstanding type 1 diabetes (T1DM) is associated with microangiopathy and poorer cognition. In the brain, T1DM is related to increased functional resting-state network (RSN) connectivity in patients without, which was decreased in patients with clinically evident microangiopathy. Subcortical structure seems affected in both patient groups. How these localized alterations affect the hierarchy of the functional network in T1DM is unknown. Eigenvector centrality mapping (ECM) and degree centrality are graph theoretical methods that allow determining the relative importance (ECM) and connectedness (degree centrality) of regions within the whole-brain network hierarchy.
methodsTherefore, ECM and degree centrality of resting-state functional MRI-scans were compared between 51 patients with, 53 patients without proliferative retinopathy, and 49 controls, and associated with RSN connectivity, subcortical gray matter volume, and cognition.
resultsIn all patients versus controls, ECM and degree centrality were lower in the bilateral thalamus and the dorsal striatum, with lowest values in patients without proliferative retinopathy (P
conclusionThe findings suggested reorganization of the hierarchy of the cortical connectivity network in patients without proliferative retinopathy, which is lost with disease progression. Centrality seems sensitive to capture early T1DM-related functional connectivity alterations, but not disease progression. Hum Brain Mapp 38:3623-3636, 2017. © 2017 Wiley Periodicals, Inc.
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