Evidence map›Paper›PMID 28429291›Full record

ArticleCritical ultrasound journal2017

Correlation of carotid blood flow and corrected carotid flow time with invasive cardiac output measurements.

Irene W Y Ma, Joshua D Caplin, Aftab Azad, Christina Wilson, Michael A Fifer, Aranya Bagchi, Andrew S Liteplo, Vicki E Noble

Registry-linked trialAbstract read
In one paragraph

Article in Critical ultrasound journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05271227 (Assessment Of Volume Responsiveness By Ultrasound Parameters Of Carotid Blood Flow In Patients With Cardiogenic Shock), which is not on this map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05271227 completednot on this mapstarted 2020, after this paper: background citation

Assessment Of Volume Responsiveness By Ultrasound Parameters Of Carotid Blood Flow In Patients With Cardiogenic Shock

TypeobservationalSponsorAlexandria UniversityRan2020 to 2021Enrolled40ConditionsCardiogenic Shock, Volume Responsiveness, UltrasoundArmsTransthoracic echocardiography and Carotid artery doppler (PHILIPS HD11 XE ultrasound device) before and after PLR test.
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  16. Carotid flow as a surrogate of the left ventricular stroke volume.Journal of clinical monitoring and computing · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Irene W Y MaDivision of Emergency Ultrasound, Department of Emergency Medicine, Massachusetts General Hospital, 326 Cambridge Street, Suite 410, Boston, MA, 02114, USA. ima@ucalgary.ca.
Joshua D CaplinCardiology Division, Department of Medicine, Massachusetts General Hospital, 15 Parkman Street #800, Boston, MA, 02114, USA.
Aftab AzadDivision of Emergency Ultrasound, Department of Emergency Medicine, Massachusetts General Hospital, 326 Cambridge Street, Suite 410, Boston, MA, 02114, USA.
Christina WilsonDivision of Emergency Ultrasound, Department of Emergency Medicine, Massachusetts General Hospital, 326 Cambridge Street, Suite 410, Boston, MA, 02114, USA.
Michael A FiferCardiology Division, Department of Medicine, Massachusetts General Hospital, 15 Parkman Street #800, Boston, MA, 02114, USA.
Aranya BagchiDepartment of Anaesthesia, Massachusetts General Hospital, 55 Fruit Street, Boston, MA, 02114, USA.
Andrew S LiteploDivision of Emergency Ultrasound, Department of Emergency Medicine, Massachusetts General Hospital, 326 Cambridge Street, Suite 410, Boston, MA, 02114, USA.
Vicki E NobleDivision of Emergency Ultrasound, Department of Emergency Medicine, Massachusetts General Hospital, 326 Cambridge Street, Suite 410, Boston, MA, 02114, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNon-invasive measures that can accurately estimate cardiac output may help identify volume-responsive patients. This study seeks to compare two non-invasive measures (corrected carotid flow time and carotid blood flow) and their correlations with invasive reference measurements of cardiac output. Consenting adult patients (n = 51) at Massachusetts General Hospital cardiac catheterization laboratory undergoing right heart catheterization between February and April 2016 were included. Carotid ultrasound images were obtained concurrently with cardiac output measurements, obtained by the thermodilution method in the absence of severe tricuspid regurgitation and by the Fick oxygen method otherwise. Corrected carotid flow time was calculated as systole time/√cycle time. Carotid blood flow was calculated as π × (carotid diameter)

resultsSingle waveform measurements of corrected flow time did not correlate with cardiac output (ρ = 0.25, 95% CI -0.03 to 0.49, p = 0.08), but an average of three waveforms correlated significantly, although weakly (ρ = 0.29, 95% CI 0.02-0.53, p = 0.046). Carotid blood flow measurements correlated moderately with cardiac output regardless of if single waveform or an average of three waveforms were used: ρ = 0.44, 95% CI 0.18-0.63, p = 0.004, and ρ = 0.41, 95% CI 0.16-0.62, p = 0.004, respectively.

conclusionsCarotid blood flow may be a better marker of cardiac output and less subject to measurements issues than corrected carotid flow time.

Indexed as

Cardiac outputCarotid blood flowCarotid flow timeCarotid ultrasound

Identifiers

PMID28429291
PMCPMC5398973

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.