ArticleMedicine, health care, and philosophy2017
Are there moral differences between maternal spindle transfer and pronuclear transfer?
Article in Medicine, health care, and philosophy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 25 citations in OpenAlex.
- Adipose Stem Cell Mitochondrial Transplantation in ART: From Biological Rationale to Clinical Milestone.Cells · 2026Review
- Mitochondrial replacement techniques for treating infertility.Journal of medical ethics · 2026Article
- Mitochondrial Replacement Techniques, the Non-Identity Problem, and Genetic Parenthood.Asian bioethics review · 2021Article
- Article
- Electrofusion Stimulation Is an Independent Factor of Chromosome Abnormality in Mice Oocytes ReconstructedFrontiers in endocrinology · 2021Article
- Lesbian motherhood and mitochondrial replacement techniques: reproductive freedom and genetic kinship.Journal of medical ethics · 2018Article
- Does egg donation for mitochondrial replacement techniques generate parental responsibilities?Journal of medical ethics · 2018Article
- Genome editing and assisted reproduction: curing embryos, society or prospective parents?Medicine, health care, and philosophy · 2018Article
- Mitochondrial manipulation in fertility clinics: Regulation and responsibility.Reproductive biomedicine & society online · 2018Article
- Mitochondrial Replacement Techniques: Genetic Relatedness, Gender Implications, and Justice.Gender and the genome · 2017Article
- Significance of Mitochondrial Dynamics in Reproductive Physiology: Current and Emerging Horizons in Mitochondrial Therapy for Assisted Reproductive Technologies.Reproductive medicine and biologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
This paper examines whether there are moral differences between the mitochondrial replacement techniques that have been recently developed in order to help women afflicted by mitochondrial DNA diseases to have genetically related children absent such conditions: maternal spindle transfer (MST) and pronuclear transfer (PNT). Firstly, it examines whether there is a moral difference between MST and PNT in terms of the divide between somatic interventions and germline interventions. Secondly, it considers whether PNT and MST are morally distinct under a therapy/creation optic. Finally, it investigates whether there is a moral difference between MST and PNT from a human embryo destruction point of view. I conclude, contra recent arguments, that regarding the first two points there is no moral differences between PNT and MST; and that regarding the third one MST is morally preferable to PNT, but only if we hold a gradualist account of the moral value of human embryos where zygotes have slight moral value.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.