Evidence map›Paper›PMID 28429201›Full record

ReviewCurrent gastroenterology reports2017

How to Approach Lymphocytic Esophagitis.

Anh D Nguyen, Kerry B Dunbar

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current gastroenterology reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. A systematic review of therapeutic options for lymphocytic esophagitis.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2025
    Pooled it
  2. Clinical, endoscopic, and histologic characteristics of lymphocytic esophagitis: a systematic review.Esophagus : official journal of the Japan Esophageal Society · 2019
    Pooled it
  3. Article
  4. A Comparative Analysis between Lymphocytic Esophagitis and Eosinophilic Esophagitis.Recent advances in inflammation & allergy drug discovery · 2026
    Article
  5. Article
  6. Lymphocytic oesophagitis: diagnosis and management.Clinical medicine (London, England) · 2023
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Lymphocytic Esophagitis: Navigating an Uncharted Territory.Journal of investigative medicine high impact case reports
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Anh D NguyenDivision of Gastroenterology and Hepatology, Department of Medicine, University of Texas Southwestern Medical Center, Dallas, TX, 75231, USA.
Kerry B DunbarEsophageal Diseases Center, Division of Gastroenterology and Hepatology, Department of Medicine, Dallas VA Medical Center and the University of Texas Southwestern Medical Center, GI Lab-CA 111-B1, Dallas VAMC, 4500 South Lancaster Road, Dallas, TX, 75231, USA. Kerry.Dunbar@utsouthwestern.edu.
The University of Texas Southwestern Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewLymphocytic esophagitis (LE) is an unusual esophageal condition defined by an increased number of lymphocytes in the esophageal epithelium. With few published studies of LE available, it is unclear whether LE is a truly distinct clinical entity or a histological manifestation of other known gastrointestinal disorders. This review summarizes recent studies of lymphocytic esophagitis. RECENT

findingsStudies have suggested that LE may be related to eosinophilic esophagitis (EoE) or a manifestation of gastroesophageal reflux disease (GERD). There is an association between LE and Crohn's disease in children, but not in adults. Patients with LE frequently report symptoms of dysphagia and GERD. Treatment options for LE are limited and involve symptom management similar to treatment of EoE or GERD, including proton pump inhibitors (PPI), swallowed topical steroids, and endoscopic dilation. With no formal definition and a variety of clinical presentations and endoscopic findings, diagnosis and management of symptomatic LE patients is challenging for clinicians.

Indexed as

EsophagitisLymphocytosisAge FactorsCrohn DiseaseDeglutition DisordersDilatationEosinophilic EsophagitisGastroesophageal RefluxHumansProton Pump InhibitorsProton Pump InhibitorsDysphagiaGastroesophageal reflux disease (GERD)Lymphocytic esophagitisLymphocytic oesophagitis

Identifiers

PMID28429201
OpenAlexW2605986793

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.