Evidence map›Paper›PMID 28429071›Full record

ReviewInternational journal of colorectal disease2017

The surgical management of radiation proctopathy.

L F McCrone, P M Neary, J Larkin, P McCormick, B Mehigan

2 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in International journal of colorectal disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04680195 phase2unknown statusnot on this mapstarted 2020, after this paper: background citation

Prospective, Open Clinical Trial of Thalidomide in the Treatment of Chronic Radiation Proctitis With Intractable Bleeding

TypeinterventionalSponsorSixth Affiliated Hospital, Sun Yat-sen UniversityRan2020 to 2022Enrolled62ConditionsChronic Radiation ProctitisArmsThalidomide
NCT05607927 phase3not yet recruitingnot on this mapstarted 2022, after this paper: background citation

Laparoscopic Proximally Extended Colorectal Resection With Two-Stage Turnbull-Cutait Pull-Through Coloanal Anastomosis for Late Complications of Chronic Radiation-induced Rectal Injury: A Prospective, Multicenter, Randomized Controlled Clinical Trail

TypeinterventionalSponsorSixth Affiliated Hospital, Sun Yat-sen UniversityRan2022 to 2028Enrolled316ConditionsChronic Radiation InjuryArmsParks surgery, PE-Bacon surgery
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

L F McCroneDepartment of Colorectal Surgery St James's University Hospital, Trinity College Dublin, Dublin, Ireland. liammccrone@rcsi.ie.
P M NearyDepartment of Colorectal Surgery St James's University Hospital, Trinity College Dublin, Dublin, Ireland.
J LarkinDepartment of Colorectal Surgery St James's University Hospital, Trinity College Dublin, Dublin, Ireland.
P McCormickDepartment of Colorectal Surgery St James's University Hospital, Trinity College Dublin, Dublin, Ireland.
B MehiganDepartment of Colorectal Surgery St James's University Hospital, Trinity College Dublin, Dublin, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is sparse evidence guiding the optimum surgical management of patients with radiation proctopathy (RP). The purpose of this review is to analyse all the literature on the surgical management of RP in order to guide physicians and surgeons as to when and what surgery should be employed for these patients.

methodsA literature search of PubMed, EMBASE, MEDLINE, Ovid, and Cochrane Library using the MeSH terms "radiation proctopathy", "proctitis", "surgical management", and related terms as keywords was performed. The review included all articles that reported on the surgical management of patients with radiation proctopathy. All relevant articles were cross-referenced for further articles and any unavailable online were retrieved from hard-copy archive libraries. Eighteen studies including one prospective cohort study, fifteen retrospective cohort studies, and three small case series are included.

conclusionSurgery is indicated for patients with RP for rectal obstruction, perforation, fistulae, or a failure of medical measures to control the symptoms of RP. Surgery centres mainly on diversion version resection. Diversion alone does not remove the damaged tissue leaving the patient at risk of continued complications including bleeding, perforation, occlusion, and abscess formation; however, major resectional surgery carries higher risks. Morbidity and mortality vary 0-44% and 0-11% for diversion only versus 0-100% and 0-14% for resectional surgery. There is no universally agreed surgical first-line approach. The data supports both resection with defunctioning stoma or diversion only as reasonable first-line surgical options for patients requiring surgery for RP.

Indexed as

HumansMorbidityProctitisRadiation InjuriesStatistics as TopicTreatment OutcomeComplicationsProctitisRadiation proctopathySurgerySurgical management

Identifiers

PMID28429071

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.