Evidence map›Paper›PMID 28428940›Full record

ArticleClinical and experimental reproductive medicine2017

Factors influencing sperm retrieval following testicular sperm extraction in nonobstructive azoospermia patients.

Peyman Salehi, Marzieh Derakhshan-Horeh, Zakiye Nadeali, Majid Hosseinzadeh, Erfan Sadeghi, Mohammad Hossein Izadpanahi, Mansour Salehi

Open access · diamondAbstract read
In one paragraph

Article in Clinical and experimental reproductive medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
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  15. MRI in the evaluation of the azoospermic male.Diagnostic and interventional radiology (Ankara, Turkey) · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Peyman SalehiShahid Beheshti Infertility Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Marzieh Derakhshan-HorehDepartment of Anatomy, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Zakiye NadealiMedical Genetics Laboratory, Al-Zahra University Hospital, Isfahan, Iran.
Majid HosseinzadehMedical Genetics Laboratory, Al-Zahra University Hospital, Isfahan, Iran.
Erfan SadeghiDepartment of Biostatistics and Epidemiology, School of Public Health, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Mohammad Hossein IzadpanahiDepartment of Urology, Isfahan University of Medical Sciences, Isfahan, Iran.
Mansour SalehiMedical Genetics Laboratory, Al-Zahra University Hospital, Isfahan, Iran.
Isfahan University of Medical Sciences · IRTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAzoospermia owing to testicular disorders is the most severe manifestation of male infertility. The main concern for patients with nonobstructive azoospermia (NOA) is the probability of successful sperm retrieval following testicular sperm extraction (TESE). Therefore, the goal of this study was to determine predictive factors correlated with sperm retrieval.

methodsWe assessed the testicular histopathological patterns, the choice of TESE surgical procedure, hormone levels, and chromosomal abnormalities in patients with NOA (n=170). The histopathology specimens were analyzed based on the histopathological patterns of hypospermatogenesis, maturation arrest, and Sertoli cell-only syndrome.

resultsThe mean rate of sperm retrieval was 48.8%. The rate of sperm retrieval was significantly higher in the hypospermatogenesis group than in the other groups (

conclusionSome parameters, including testicular histopathology patterns, FSH levels, testicular volume, and method of TESE surgery, may be able to predict the chances of obtaining spermatozoa in patients with NOA. However, despite the efficiency of some predictive models, the hope of retrieving any functioning spermatozoa may be sufficient to disregard predictive factors of the success of intracytoplasmic sperm injection in these patients.

Indexed as

AzoospermiaPathologySperm retrieval

Identifiers

PMID28428940
PMCPMC5395548
OpenAlexW2605759983

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.