Evidence map›Paper›PMID 28428835›Full record

ArticlePlasma medicine2016

Aqueous Plasma Pharmacy: Preparation Methods, Chemistry, and Therapeutic Applications.

Jessica M Joslin, James R McCall, Justin P Bzdek, Derek C Johnson, Brooks M Hybertson

Abstract read
In one paragraph

Article in Plasma medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jessica M JoslinSymbios Technologies, Inc., 3185 Rampart Road, Bldg. A, Colorado State University Research Innovation Center, Fort Collins, CO 80523.
James R McCallSymbios Technologies, Inc., 3185 Rampart Road, Bldg. A, Colorado State University Research Innovation Center, Fort Collins, CO 80523.
Justin P BzdekSymbios Technologies, Inc., 3185 Rampart Road, Bldg. A, Colorado State University Research Innovation Center, Fort Collins, CO 80523.
Derek C JohnsonSymbios Technologies, Inc., 3185 Rampart Road, Bldg. A, Colorado State University Research Innovation Center, Fort Collins, CO 80523.
Brooks M HybertsonSymbios Technologies, Inc., 3185 Rampart Road, Bldg. A, Colorado State University Research Innovation Center, Fort Collins, CO 80523.

Funding

Continuous Production of Organic Peroxyacid Antimicrobial Agents for Wound Care Using a Selective Plasma Oxidation ReactorR43GM121092 · NIGMS · SYMBIOS TECHNOLOGIES, INC · PI JOSLIN, JESSICA · 2016 to 2016
$225k
Plasma Generation of Aqueous Chemotherapeutic SolutionsR43CA203273 · NCI · SYMBIOS TECHNOLOGIES, INC · PI JOSLIN, JESSICA · 2016 to 2016
$225k
NCI NIH HHS R43 CA203273NIGMS NIH HHS R43 GM121092
6 · The paper itself

Abstract

Plasma pharmacy is a subset of the broader field of plasma medicine. Although not strictly defined, the term aqueous plasma pharmacy (APP) is used to refer to the generation and distribution of reactive plasma-generated species in an aqueous solution followed by subsequent administration for therapeutic benefits. APP attempts to harness the therapeutic effects of plasma-generated oxidant species within aqueous solution in various applications, such as disinfectant solutions, cell proliferation related to wound healing, and cancer treatment. The subsequent use of plasma-generated solutions in the APP approach facilitates the delivery of reactive plasma species to internal locations within the body. Although significant efforts in the field of plasma medicine have concentrated on employing direct plasma plume exposure to cells or tissues, here we focus specifically on plasma discharge in aqueous solution to render the solution biologically active for subsequent application. Methods of plasma discharge in solution are reviewed, along with aqueous plasma chemistry and the applications for APP. The future of the field also is discussed regarding necessary research efforts that will enable commercialization for clinical deployment.

Indexed as

aqueous plasma pharmacyplasma-activated mediumplasma-activated solutionplasma medicineplasma pharmacyplasma-stimulated medium

Identifiers

PMID28428835
PMCPMC5394942

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.