Evidence map›Paper›PMID 28428823›Full record

ArticleBiotechnology for biofuels2017

Combining manipulation of transcription factors and overexpression of the target genes to enhance lignocellulolytic enzyme production in

Liwei Gao, Zhonghai Li, Chengqiang Xia, Yinbo Qu, Meng Liu, Piao Yang, Lele Yu, Xin Song

Abstract read
In one paragraph

Article in Biotechnology for biofuels, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

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  14. Purification and characterization of the low molecular weight xylanase from Bacillus cereus L-1.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Liwei GaoState Key Laboratory of Microbial Technology, School of Life Science, Shandong University, Jinan, 250100 Shandong China.
Zhonghai LiState Key Laboratory of Microbial Technology, School of Life Science, Shandong University, Jinan, 250100 Shandong China.
Chengqiang XiaState Key Laboratory of Microbial Technology, School of Life Science, Shandong University, Jinan, 250100 Shandong China.
Yinbo QuState Key Laboratory of Microbial Technology, School of Life Science, Shandong University, Jinan, 250100 Shandong China.
Meng LiuState Key Laboratory of Microbial Technology, School of Life Science, Shandong University, Jinan, 250100 Shandong China.
Piao YangState Key Laboratory of Microbial Technology, School of Life Science, Shandong University, Jinan, 250100 Shandong China.
Lele YuState Key Laboratory of Microbial Technology, School of Life Science, Shandong University, Jinan, 250100 Shandong China.
Xin SongState Key Laboratory of Microbial Technology, School of Life Science, Shandong University, Jinan, 250100 Shandong China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLignocellulolytic enzymes are the main enzymes to saccharify lignocellulose from renewable plant biomass in the bio-based economy. The production of these enzymes is transcriptionally regulated by multiple transcription factors. We previously engineered

resultsHere, we verified that a point mutation XlnR

conclusionsThe results illustrated that combinational manipulation of the involved transcription factors and their target genes was a viable strategy for efficient production of lignocellulolytic enzymes in filamentous fungi. The striking negative effect of XlnR

Indexed as

CellulaseHemicellulasePenicillium oxalicumTranscription factor

Identifiers

PMID28428823
PMCPMC5397729

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.