ArticleAnnals of general psychiatry2017
Is low total cholesterol levels associated with suicide attempt in depressive patients?
Article in Annals of general psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
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Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.
- Association between serum lipid concentrations and attempted suicide in patients with major depressive disorder: A meta-analysis.PloS one · 2020Pooled it
- The prevalence, metabolic disturbances and clinical correlates of recent suicide attempts in Chinese inpatients with major depressive disorder.BMC psychiatry · 2019Trial
- Association between Apolipoprotein B (ApoB) and suicidal ideation: a cross-sectional study and Mendelian randomization analysis.Annals of general psychiatry · 2026Article
- A Contemporary Perspective on Long-Term Complications of Bariatric Surgery.Obesity surgery · 2026Review
- Agitation/excitement in male patients with treatment-resistant schizophrenia is associated with lower total cholesterol levels.Frontiers in psychiatry · 2026Article
- Towards Objective Major Depressive Disorder Detection: a Systematic Review and Meta-Analysis of Diagnostic Biomarkers.The Psychiatric quarterly · 2025Review
- Exploring the role of impulsivity, aggression, lipid profiles, and inflammatory markers in suicide attempts: a crossdiagnostic study.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2025Article
- Biological Basis for the Formation of Suicidal Behavior: A Review.Medical journal of the Islamic Republic of Iran · 2025Review
- Sex differences of the lipid profile, impulsivity and suicidality in psychiatric inpatients.Frontiers in psychiatry · 2025Article
- Article
- The association between child maltreatment, cognitive reappraisal, negative coping styles, and non-suicidal self-injury in adolescents with major depressive disorder.BMC psychiatry · 2024Article
- Distinct correlation network of clinical characteristics in suicide attempters having adolescent major depressive disorder with non-suicidal self-injury.Translational psychiatry · 2024Article
- Development and validation of a nomogram for suicide attempts in patients with first-episode drug-naïve major depressive disorder.Frontiers in psychiatry · 2024Article
- Tissue-Specific Oxysterols as Predictors of Antidepressant (Escitalopram) Treatment Response in Patients With Major Depressive Disorder.Biological psychiatry global open science · 2023Article
- Beyond BMI: cardiometabolic measures as predictors of impulsivity and white matter changes in adolescents.Brain structure & function · 2023Article
- Association rule mining of real-world data: Uncovering links between race, glycemic control, lipid profiles, and suicide attempts in individuals with diabetes.Informatics in medicine unlocked · 2023Article
- Age-specific associations between serum cholesterol levels and suicidal behaviors in patients with depressive disorders: A naturalistic prospective observational cohort study.Frontiers in psychiatry · 2023Article
- Suicide attempt rate and the risk factors in young, first-episode and drug-naïve Chinese Han patients with major depressive disorder.BMC psychiatry · 2022Article
- Association between fasting blood glucose and thyroid stimulating hormones and suicidal tendency and disease severity in patients with major depressive disorder.Bosnian journal of basic medical sciences · 2022Article
- Cardiovascular therapeutics: A new potential for anxiety treatment?Medicinal research reviews · 2022Review
Corrections and comments
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Authors and funding
13 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients with major depressive disorder (MDD) have a high risk of suicide. Many pathophysiological factors involved in MDD and suicide such us a low cholesterol levels have been associated with MDD and increased vulnerability to suicide. In this study, we investigate the relation between lipid parameters and suicide risk in patients with MDD.
methodsPlasma levels of total cholesterol, triglycerides, and high-density lipoprotein cholesterol (HDL-c) and low-density lipoprotein cholesterol (LDL-c) were determined in 160 patients meeting the DSM-IV-TR criteria for MDD (110 patients without suicidal behavior and 52 suicidal attempters) and 151 healthy controls.
resultsA significant decrease in plasma cholesterol levels was observed in the group of suicidal depressive patients compared to those without suicidal behavior (
conclusionsOur study showed a significant decrease in plasma cholesterol levels in suicidal patients. This result support the hypothesis of the association of low plasma cholesterol level and suicidal behavior in patients with major depressive disorder.
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