Evidence map›Paper›PMID 28428423›Full record

ArticleScience (New York, N.Y.)2017

Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat.

Thomas J Park, Jane Reznick, Bethany L Peterson, Gregory Blass, Damir Omerbašić, Nigel C Bennett, P Henning J L Kuich, Christin Zasada, Brigitte M Browe, Wiebke Hamann and 15 more

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Science (New York, N.Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 207 papers.

0numbers the graph read from it
0cells of the map it votes in
207citing papers in PubMed
49.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

207 citing papers in PubMed, 639 citations in OpenAlex.

  1. A moveable feast: Neurons become less picky eaters after hibernation.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  11. IGF-mediated glucose signalling is retained in adult naked mole-rats.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2026
    Article
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  13. Brain-derived ketone bodies can replace glucose to power neural function.bioRxiv : the preprint server for biology · 2026
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  14. Article
  15. Review
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147 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

25 authors at 4 institutions in 4 countries.

Thomas J ParkLaboratory of Integrative Neuroscience, Department of Biological Sciences, University of Illinois at Chicago, Chicago, IL 60607, USA. glewin@mdc-berlin.de tpark@uic.edu.ORCID 0000-0002-2447-2948
Jane ReznickMolecular Physiology of Somatic Sensation, Max Delbrück Center for Molecular Medicine, Berlin, Germany.ORCID 0000-0001-7921-5466
Bethany L PetersonLaboratory of Integrative Neuroscience, Department of Biological Sciences, University of Illinois at Chicago, Chicago, IL 60607, USA.ORCID 0000-0002-0853-5996
Gregory BlassLaboratory of Integrative Neuroscience, Department of Biological Sciences, University of Illinois at Chicago, Chicago, IL 60607, USA.ORCID 0000-0002-4549-4281
Damir OmerbašićMolecular Physiology of Somatic Sensation, Max Delbrück Center for Molecular Medicine, Berlin, Germany.ORCID 0000-0003-1839-4856
Nigel C BennettDepartment of Zoology and Entomology, University of Pretoria, Pretoria, Republic of South Africa.
P Henning J L KuichIntegrative Proteomics and Metabolomics, Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine, Berlin, Germany.
Christin ZasadaIntegrative Proteomics and Metabolomics, Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine, Berlin, Germany.ORCID 0000-0003-1547-8317
Brigitte M BroweLaboratory of Integrative Neuroscience, Department of Biological Sciences, University of Illinois at Chicago, Chicago, IL 60607, USA.ORCID 0000-0001-7235-2986
Wiebke HamannNeuromuscular and Cardiovascular Cell Biology, Max Delbrück Center for Molecular Medicine, Berlin, Germany.ORCID 0000-0002-6525-762X
Daniel T ApplegateLaboratory of Integrative Neuroscience, Department of Biological Sciences, University of Illinois at Chicago, Chicago, IL 60607, USA.ORCID 0000-0003-4904-5165
Michael H RadkeNeuromuscular and Cardiovascular Cell Biology, Max Delbrück Center for Molecular Medicine, Berlin, Germany.ORCID 0000-0003-0112-9917
Tetiana KostenMolecular Physiology of Somatic Sensation, Max Delbrück Center for Molecular Medicine, Berlin, Germany.
Heike LutermannDepartment of Zoology and Entomology, University of Pretoria, Pretoria, Republic of South Africa.ORCID 0000-0002-7521-2302
Victoria GavaghanLaboratory of Integrative Neuroscience, Department of Biological Sciences, University of Illinois at Chicago, Chicago, IL 60607, USA.ORCID 0000-0003-1117-0470
Ole EigenbrodMolecular Physiology of Somatic Sensation, Max Delbrück Center for Molecular Medicine, Berlin, Germany.
Valérie BégayMolecular Physiology of Somatic Sensation, Max Delbrück Center for Molecular Medicine, Berlin, Germany.
Vince G AmorosoLaboratory of Integrative Neuroscience, Department of Biological Sciences, University of Illinois at Chicago, Chicago, IL 60607, USA.ORCID 0000-0002-1438-846X
Vidya GovindLaboratory of Integrative Neuroscience, Department of Biological Sciences, University of Illinois at Chicago, Chicago, IL 60607, USA.ORCID 0000-0001-5840-9472
Richard D MinshallDepartments of Anesthesiology and Pharmacology, University of Illinois at Chicago, Chicago, IL 60612, USA.ORCID 0000-0003-3164-475X
Ewan St J SmithDepartment of Pharmacology, University of Cambridge, Cambridge CB2 1PD, UK.ORCID 0000-0002-2699-1979
John LarsonDepartment of Psychiatry, University of Illinois at Chicago, Chicago, IL 60612, USA.
Michael GotthardtNeuromuscular and Cardiovascular Cell Biology, Max Delbrück Center for Molecular Medicine, Berlin, Germany.
Stefan KempaIntegrative Proteomics and Metabolomics, Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine, Berlin, Germany.ORCID 0000-0002-0696-9299
Gary R LewinMolecular Physiology of Somatic Sensation, Max Delbrück Center for Molecular Medicine, Berlin, Germany. glewin@mdc-berlin.de tpark@uic.edu.ORCID 0000-0002-2890-6352
Max Delbrück Center · DEUniversity of Illinois Chicago · USUniversity of Pretoria · ZAUniversity of Cambridge · GB

Funding

Src Regulation of Lung Endothelial Barrier FunctionR01HL071626 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MINSHALL, RICHARD D · 2003 to 2011
$2.4M
European Research Council 294678NHLBI NIH HHS R01 HL071626
6 · The paper itself

Abstract

The African naked mole-rat's (

Indexed as

Adaptation, PhysiologicalAnaerobiosisGlycolysisAnimalsBrainFructokinasesFructoseGlucose Transporter Type 5Lactic AcidMiceMole RatsMyocardiumOxygenSucroseFructokinasesFructoseGlucose Transporter Type 5ketohexokinaseLactic AcidOxygenSucrose

Identifiers

PMID28428423
OpenAlexW2606455791

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.