Evidence map›Paper›PMID 28428282›Full record

ReviewCancer research2017

Whither Radioimmunotherapy: To Be or Not To Be?

Damian J Green, Oliver W Press

Open access · bronzeAbstract readReview
In one paragraph

Review in Cancer research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 61 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. CD20-Targeted α-Radionuclides Synergize with Immune Checkpoint Inhibition to Treat Murine Lymphoma.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Article
  5. Review
  6. Review
  7. Article
  8. Pretargeting: A Path Forward for Radioimmunotherapy.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Review
  9. Article
  10. Article
  11. Review
  12. National Cancer Institute support for targeted alpha-emitter therapy.European journal of nuclear medicine and molecular imaging · 2021
    Review
  13. Review
  14. Stabilization of anACS omega · 2021
    Article
  15. Review
  16. Article
  17. Article
  18. Tissue Factor-Targeted ImmunoPET Imaging and Radioimmunotherapy of Anaplastic Thyroid Cancer.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Damian J GreenClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington. dgreen@fhcrc.org.
Oliver W PressClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
University of Washington · US

Funding

TREATMENT OF B-CELL LYMPHOMAP01CA044991 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BALDWIN, JANELL · 1988 to 2015
$29.3M
Radioimmunotherapy Combinations for B-cell MalignancyR01CA076287 · NCI · UNIVERSITY OF WASHINGTON · PI GREEN, DAMIAN J. · 1998 to 2025
$8.1M
CD45 Pretargeted Radioimmunotherapy for AMLR01CA109663 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI PRESS, OLIVER W. · 2004 to 2013
$2.9M
Anti-CD38 targeted alpha emitter radioimmunotherapy to eliminate multiple myelomaR01CA205248 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI GREEN, DAMIAN J. · 2017 to 2023
$2.8M
CD38 Pretargeted Radioimmunotherapy for MyelomaR01CA154897 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI GREEN, DAMIAN J. · 2011 to 2015
$1.8M
Bispecific Antibody Engineering for AML RITR01CA136639 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI PRESS, OLIVER W. · 2009 to 2013
$1.6M
Radioimmunotherapy for Multiple MyelomaK08CA151682 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI GREEN, DAMIAN J. · 2010 to 2014
$848k
Targeted Radiotherapy with 90Y-BC8 Monclonal Antibody, Fludarabine and TBI FollowR21CA155911 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI GREEN, DAMIAN J. · 2011 to 2012
$693k
NCI NIH HHS K08 CA151682NCI NIH HHS P01 CA044991NCI NIH HHS R01 CA076287NCI NIH HHS R01 CA109663NCI NIH HHS R01 CA136639NCI NIH HHS R01 CA154897NCI NIH HHS R01 CA205248NCI NIH HHS R21 CA155911
6 · The paper itself

Abstract

Therapy of cancer with radiolabeled monoclonal antibodies has produced impressive results in preclinical experiments and in clinical trials conducted in radiosensitive malignancies, particularly B-cell lymphomas. Two "first-generation," directly radiolabeled anti-CD20 antibodies,

Indexed as

RadioimmunotherapyAntibodies, MonoclonalHumansImmunoconjugatesLymphoma, B-CellRadiopharmaceuticalsYttrium RadioisotopesAntibodies, Monoclonalibritumomab tiuxetanImmunoconjugatesRadiopharmaceuticalstositumomab I-131Yttrium Radioisotopes

Identifiers

PMID28428282
PMCPMC5413412
OpenAlexW2605785971

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.