Evidence map›Paper›PMID 28428252›Full record

Observational studyJournal of applied physiology (Bethesda, Md. : 1985)2017

Low-frequency blood pressure oscillations and inotrope treatment failure in premature infants.

Zachary A Vesoulis, Jessica Hao, Christopher McPherson, Nathalie M El Ters, Amit M Mathur

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in Journal of applied physiology (Bethesda, Md. : 1985), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Observational
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Zachary A VesoulisDivision of Newborn Medicine, Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri; and vesoulis_z@kids.wustl.edu.ORCID http://orcid.org/0000-0001-8290-0069
Jessica HaoDivision of Newborn Medicine, Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri; and.
Christopher McPhersonDivision of Newborn Medicine, Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri; and.
Nathalie M El TersDivision of Newborn Medicine, Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri; and.
Amit M MathurDivision of Newborn Medicine, Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri; and.
Mallinckrodt (United States) · USSt. Louis Children's Hospital · US

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
Washington University Institute of Clinical and Translational Sciences (KL2) KL2TR002346 · NCATS · WASHINGTON UNIVERSITY · PI Dominic N Reeds · 2017 to 2026
$14.0M
Washington University Institute of Clinical and Translational SciencesKL2TR000450 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$8.8M
Washington University Intellectual and Developmental Disabilities Research Center-Administrative Down Syndrome SupplementU54HD087011 · NICHD · WASHINGTON UNIVERSITY · PI MOLEY, KELLE H · 2015 to 2019
$7.1M
Washington University Intellectual and Developmental Disabilities Research CenterP30HD062171 · NICHD · WASHINGTON UNIVERSITY · PI NEIL, JEFFREY J. · 2010 to 2014
$4.3M
NCATS NIH HHS KL2 TR000450NCATS NIH HHS KL2 TR002346NCATS NIH HHS UL1 TR000448NCATS NIH HHS UL1 TR002345NICHD NIH HHS P30 HD062171NICHD NIH HHS U54 HD087011
6 · The paper itself

Abstract

The underlying mechanism as to why some hypotensive preterm infants do not respond to inotropic medications remains unclear. For these infants, we hypothesize that impaired vasomotor function is a significant factor and is manifested through a decrease in low-frequency blood pressure variability across regulatory components of vascular tone. Infants born ≤28 wk estimated gestational age underwent prospective recording of mean arterial blood pressure for 72 h after birth. After error correction, root-mean-square spectral power was calculated for each valid 10-min data frame across each of four frequency bands (

Indexed as

Blood PressureCardiotonic AgentsCohort StudiesDatabases, FactualFemaleHumansHypotensionInfant, NewbornInfant, PrematureMaleMyocardial ContractionTreatment FailureCardiotonic Agentsblood pressureinotropesprematurityspectral analysis

Identifiers

PMID28428252
PMCPMC6157481
OpenAlexW2606379132

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.