Evidence map›Paper›PMID 28428193›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2017

PD-L1 Expression in Melanoma: A Quantitative Immunohistochemical Antibody Comparison.

Joel C Sunshine, Peter L Nguyen, Genevieve J Kaunitz, Tricia R Cottrell, Sneha Berry, Jessica Esandrio, Haiying Xu, Aleksandra Ogurtsova, Karen B Bleich, Toby C Cornish and 3 more

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed, 2 pooled it
8.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 2 syntheses or guidelines pooled it, 159 citations in OpenAlex.

  1. Pooled it
  2. "Interchangeability" of PD-L1 immunohistochemistry assays: a meta-analysis of diagnostic accuracy.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2020
    Pooled it
  3. Trial
  4. Trial
  5. Clinical outcomes of prexasertib monotherapy in recurrentJournal for immunotherapy of cancer · 2020
    Trial
  6. Trial
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Prognostic Biomarkers in Evolving Melanoma Immunotherapy.American journal of clinical dermatology · 2025
    Review
  16. CD133Nature communications · 2025
    Article
  17. Article
  18. Article
  19. Review
  20. Article

31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Joel C SunshineDepartment of Dermatology, Johns Hopkins University and the Bloomberg Kimmel Institute for Cancer Immunotherapy, Baltimore, Maryland.
Peter L NguyenDepartment of Dermatology, Johns Hopkins University and the Bloomberg Kimmel Institute for Cancer Immunotherapy, Baltimore, Maryland.
Genevieve J KaunitzDepartment of Dermatology, Johns Hopkins University and the Bloomberg Kimmel Institute for Cancer Immunotherapy, Baltimore, Maryland.
Tricia R CottrellDepartment of Pathology, Johns Hopkins University and the Bloomberg Kimmel Institute for Cancer Immunotherapy, Baltimore, Maryland.
Sneha BerryDepartment of Oncology, Johns Hopkins University and the Bloomberg Kimmel Institute for Cancer Immunotherapy, Baltimore, Maryland.
Jessica EsandrioDepartment of Dermatology, Johns Hopkins University and the Bloomberg Kimmel Institute for Cancer Immunotherapy, Baltimore, Maryland.
Haiying XuDepartment of Dermatology, Johns Hopkins University and the Bloomberg Kimmel Institute for Cancer Immunotherapy, Baltimore, Maryland.
Aleksandra OgurtsovaDepartment of Dermatology, Johns Hopkins University and the Bloomberg Kimmel Institute for Cancer Immunotherapy, Baltimore, Maryland.
Karen B BleichDepartment of Radiation Oncology, Johns Hopkins University and the Bloomberg Kimmel Institute for Cancer Immunotherapy, Baltimore, Maryland.
Toby C CornishDepartment of Pathology, Johns Hopkins University and the Bloomberg Kimmel Institute for Cancer Immunotherapy, Baltimore, Maryland.
Evan J LipsonDepartment of Radiation Oncology, Johns Hopkins University and the Bloomberg Kimmel Institute for Cancer Immunotherapy, Baltimore, Maryland.
Robert A AndersDepartment of Pathology, Johns Hopkins University and the Bloomberg Kimmel Institute for Cancer Immunotherapy, Baltimore, Maryland.
Janis M TaubeDepartment of Dermatology, Johns Hopkins University and the Bloomberg Kimmel Institute for Cancer Immunotherapy, Baltimore, Maryland. jtaube1@jhmi.edu.
Bloomberg (United States) · US

Funding

PD-1/PD-L1 modulation in cancer therapyR01CA142779 · NCI · JOHNS HOPKINS UNIVERSITY · PI PARDOLL, DREW M., TAUBE, JANIS M · 2010 to 2025
$8.2M
Opportunities for Pathology Trainees in Cancer ResearchT32CA193145 · NCI · JOHNS HOPKINS UNIVERSITY · PI ANDERS, ROBERT A., EBERHART, CHARLES G · 2015 to 2025
$2.6M
NCI NIH HHS R01 CA142779NCI NIH HHS T32 CA193145
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antibodies, MonoclonalB7-H1 AntigenBiomarkers, TumorCell Line, TumorHumansImmunohistochemistryMelanomaPathology, ClinicalReproducibility of ResultsSensitivity and SpecificityAntibodies, MonoclonalB7-H1 AntigenBiomarkers, TumorCD274 protein, human

Identifiers

PMID28428193
PMCPMC6175606
OpenAlexW2606432770

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.