Evidence map›Paper›PMID 28428183›Full record

ArticleBMJ open2017

Risk and burden of adverse intrapartum-related outcomes associated with non-cephalic and multiple birth in rural Nepal: a prospective cohort study.

Naoko Kozuki, Joanne Katz, Subarna K Khatry, James M Tielsch, Steven C LeClerq, Luke C Mullany

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01177111 (Impact of Sunflower Seed Oil Massage on Neonatal Mortality and Morbidity in Nepal), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01177111 phase3completednot on this map

Impact of Sunflower Seed Oil Massage on Neonatal Mortality and Morbidity in Nepal

TypeinterventionalSponsorJohns Hopkins Bloomberg School of Public HealthRan2010 to 2017Enrolled29,260ConditionsNeonatal Mortality, Neonatal SepsisArmsSunflower seed oil, Mustard seed oil
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Naoko KozukiDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID 0000-0003-2850-3956
Joanne KatzDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Subarna K KhatryNepal Nutrition Intervention Project-Sarlahi (NNIPS), Lalitpur, Nepal.
James M TielschDepartment of Global Health, George Washington University Milken Institute School of Public Health, Washington, District of Columbia, USA.
Steven C LeClerqDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Luke C MullanyDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Johns Hopkins University · USMilken Institute · US

Funding

Impact of Sunflower Oil Massage on Neonatal Mortality in NepalR01HD060712 · NICHD · JOHNS HOPKINS UNIVERSITY · PI MULLANY, LUKE C · 2009 to 2013
$2.9M
NICHD NIH HHS R01 HD060712
6 · The paper itself

Abstract

objectivesIntrapartum-related complications are the second leading cause of neonatal death worldwide. We estimate the community-level risk and burden of intrapartum-related fetal/neonatal mortality and morbidity associated with non-cephalic and multiple birth in rural Sarlahi District, Nepal.

designCommunity-based prospective cohort study.

settingRural Sarlahi District, Nepal.

participantsPregnant women residing in the study area.

methodsWe collected data on maternal background characteristics, conditions during labour and delivery, fetal presentation and multiple birth during home visits. We ran log-binomial regression models to estimate the associations between non-cephalic/multiple births and fresh stillbirth, early neonatal mortality and signs of neonatal encephalopathy, respectively, and calculated the per cent attributable fraction. To better understand the context under which these adverse birth outcomes are occurring, we also collected data on maternal awareness of non-cephalic presentation and multiple gestation prior to delivery. PRIMARY OUTCOME MEASURES: Risk of experiencing fresh stillbirth, early neonatal encephalopathy and early neonatal mortality associated with non-cephalic and multiple birth, respectively.

resultsNon-cephalic presentation had a particularly high risk of fresh stillbirth (aRR 12.52 (95% CI 7.86 to 19.95), reference: cephalic presentation). 20.2% of all fresh stillbirths were associated with non-cephalic presentation. For multiple births, there was a fourfold increase in early neonatal mortality (aRR: 4.57 (95% CI 1.44 to 14.50), reference: singleton births). 3.4% of early neonatal mortality was associated with multiple gestation.

conclusionsGlobally and in Nepal, a large percentage of stillbirths and neonatal mortality is associated with intrapartum-related complications. Despite the low incidence of non-cephalic and multiple birth, a notable proportion of adverse intrapartum-related outcomes is associated with these conditions. As the proportion of neonatal deaths attributable to intrapartum-related complications continues to rise, there is a need to investigate how best to advance diagnostic capacity and management of these conditions. TRIAL REGISTRATION NUMBER: NCT01177111; pre-results.

Indexed as

Breech PresentationPregnancy, MultiplePregnant PeopleAdultDelivery, ObstetricFemaleHumansIncidenceInfantInfant MortalityInfant, NewbornLabor, ObstetricNepalPregnancyPrenatal CareProspective Studiesbreechmultiple gestationneonatal mortalityNepalnon-cephalic presentationstillbirth

Identifiers

PMID28428183
PMCPMC5663011
OpenAlexW2606203480

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.