Evidence map›Paper›PMID 28428055›Full record

ReviewFrontiers in neuroendocrinology2017

Sex differences in cardiovascular disease - Impact on care and outcomes.

K H Humphries, M Izadnegahdar, T Sedlak, J Saw, N Johnston, K Schenck-Gustafsson, R U Shah, V Regitz-Zagrosek, J Grewal, V Vaccarino and 2 more

Registry-linked trialAbstract readReview
In one paragraph

Review in Frontiers in neuroendocrinology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06810661 (Managing Frailty Through Mobilization in Males and Female Inpatients With Cardiovascular Disease), which is not on this map. Cited by 127 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
127citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06810661 narecruitingnot on this mapstarted 2025, after this paper: background citation

Managing Frailty Through Mobilization in Males and Female Inpatients With Cardiovascular Disease

TypeinterventionalSponsorUniversité de SherbrookeRan2025 to 2026Enrolled60ConditionsCardiovascular Diseases, FrailtyArmsMobility promotion
3 · Its place in the literature

Who cites it

127 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Sex differences in cardiovascular disease and dysregulation in Down syndrome.American journal of physiology. Heart and circulatory physiology · 2023
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Ovarian hormones moderate systolic hypertension in femaleAmerican journal of physiology. Renal physiology · 2026
    Article
  13. Observational
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Ovarian Hormones Moderate Systolic Hypertension in FemalebioRxiv : the preprint server for biology · 2025
    Article

67 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

K H HumphriesDivision of Cardiology, University of British Columbia, Vancouver, Canada; BC Centre for Improved Cardiovascular Health, Vancouver, Canada. Electronic address: karin.humphries@ubc.ca.
M IzadnegahdarBC Centre for Improved Cardiovascular Health, Vancouver, Canada.
T SedlakDivision of Cardiology, University of British Columbia, Vancouver, Canada.
J SawDivision of Cardiology, University of British Columbia, Vancouver, Canada.
N JohnstonDepartment of Medical Sciences, Cardiology, Uppsala University Hospital, Uppsala, Sweden.
K Schenck-GustafssonDepartment of Medicine, Cardiac Unit and Centre for Gender Medicine, Karolinska University Hospital and Karolinska Institutet, Sweden.
R U ShahDivision of Cardiovascular Medicine, University of Utah School of Medicine, USA.
V Regitz-ZagrosekInstitute of Gender in Medicine (GIM) and Center for Cardiovascular Research (CCR) Charité, University Medicine Berlin and DZHK, Partner Site Berlin, Germany.
J GrewalDivision of Cardiology, University of British Columbia, Vancouver, Canada.
V VaccarinoDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA; Department of Medicine, School of Medicine, Emory University, Atlanta, GA, USA.
J WeiBarbra Streisand Women's Heart Center, Cedars-Sinai Heart Institute, Los Angeles, CA, USA.
C N Bairey MerzBarbra Streisand Women's Heart Center, Cedars-Sinai Heart Institute, Los Angeles, CA, USA.

Funding

ZONA-FREE HAMSTER OVA ASSAY AS AN INDICATOR OF MALE FERTILITYM01RR000425 · NCRR · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI ANDERSON, GAIL V · 1985 to 2011
$74.2M
UCLA Clinical and Translational Science InstituteUL1TR000124 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2012 to 2015
$57.0M
Using social networks to map and evaluate team science across CTSA hubsUL1TR001427 · NCATS · UNIVERSITY OF FLORIDA · PI MITCHELL, DUANE A. · 2015 to 2024
$37.2M
UF Clinical and Translational Science AwardUL1TR000064 · NCATS · UNIVERSITY OF FLORIDA · PI NELSON, DAVID R · 2012 to 2014
$12.2M
Vascular Responses During Mental StressP01HL101398 · NHLBI · EMORY UNIVERSITY · PI SHEPS, DAVID SAMUEL · 2010 to 2015
$11.0M
Mental Stress and Myocardial Ischemia after MI: Sex Differences, Mechanisms and PrognosisR01HL109413 · NHLBI · EMORY UNIVERSITY · PI VACCARINO, VIOLA · 2012 to 2023
$6.9M
Women's Ischemia Syndrome Evaluation (WISE) Coronary Vascular DysfunctionR01HL090957 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI BAIREY MERZ, CATHLEEN NOEL, PEPINE, CARL J · 2008 to 2013
$3.5M
PTSD and Ischemic Heart Disease Progression: A Longitudinal Twin StudyR01HL125246 · NHLBI · EMORY UNIVERSITY · PI VACCARINO, VIOLA · 2015 to 2018
$3.4M
Sleep Disturbance as a Mechanism for Ischemic Heart Disease in PTSDR01HL136205 · NHLBI · EMORY UNIVERSITY · PI VACCARINO, VIOLA · 2017 to 2020
$3.1M
Mind-Body Interactions in Cardiovascular DiseaseK24HL077506 · NHLBI · EMORY UNIVERSITY · PI VACCARINO, VIOLA · 2004 to 2013
$1.5M
Behavioral Medicine and Cardiovascular Research TrainingT32HL069751 · NHLBI · HENRY M. JACKSON FDN FOR THE ADV MIL/MED · PI KRANTZ, DAVID S. · 2003 to 2007
$1.2M
Functional MRI of the pharyngeal airwayR01HL068162 · NHLBI · UNIVERSITY OF ARIZONA · PI FREGOSI, RALPH FRANK · 2003 to 2005
$899k
NCATS NIH HHS UL1 TR000064NCATS NIH HHS UL1 TR000124NCATS NIH HHS UL1 TR001427NCRR NIH HHS M01 RR000425NHLBI NIH HHS K23 HL105787NHLBI NIH HHS K24 HL077506NHLBI NIH HHS N01 HV068161NHLBI NIH HHS N01 HV068162NHLBI NIH HHS N01 HV068163NHLBI NIH HHS N01 HV068164NHLBI NIH HHS P01 HL101398NHLBI NIH HHS R01 HL090957NHLBI NIH HHS R01 HL109413NHLBI NIH HHS R01 HL125246NHLBI NIH HHS R01 HL136205NHLBI NIH HHS R21 HL093665NHLBI NIH HHS T32 HL069751NIA NIH HHS R03 AG032631
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Sex CharacteristicsSmokingAnimalsCardiovascular DiseasesFemaleHumansMaleMyocardial IschemiaRisk FactorsSex FactorsCardiovascular diseaseGenderSexWomen

Identifiers

PMID28428055
PMCPMC5506856

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.