Evidence map›Paper›PMID 28427790›Full record

ReviewAmerican journal of kidney diseases : the official journal of the National Kidney Foundation2017

Exercise and CKD: Skeletal Muscle Dysfunction and Practical Application of Exercise to Prevent and Treat Physical Impairments in CKD.

Baback Roshanravan, Jorge Gamboa, Kenneth Wilund

Abstract readCase ReportsReview
PubMed Full text at PMC Publisher
In one paragraph

Review in American journal of kidney diseases : the official journal of the National Kidney Foundation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 112 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
112citing papers in PubMed, 11 pooled it
11.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

112 citing papers in PubMed, 11 syntheses or guidelines pooled it, 227 citations in OpenAlex.

  1. Properties of Measurements of Patient-Reported Outcome Measures Physical Activity Assessment in Chronic Kidney Disease: A Systematic Review.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2025
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  8. Osteoporosis in Patients with Chronic Kidney Diseases: A Systemic Review.International journal of molecular sciences · 2020
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52 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Baback RoshanravanDivision of Nephrology, Department of Medicine, University of Washington Kidney Research Institute, Seattle, WA. Electronic address: broshanr@uw.edu.
Jorge GamboaVanderbilt University Medical Center, Nashville, TN.
Kenneth WilundDepartment of Kinesiology and Community Health, University of Illinois, Urbana, IL.
University of Washington · USUrbana University · USVanderbilt University Medical Center · US

Funding

Skeletal muscle dysfunction in persons with chronic kidney diseaseK23DK099442 · NIDDK · UNIVERSITY OF WASHINGTON · PI ROSHANRAVAN, BABACK · 2013 to 2017
$777k
Mitochondrial Dysfunction in Chronic Kidney DiseaseK23DK100533 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GAMBOA, JORGE LUIS · 2013 to 2017
$763k
NIDDK NIH HHS K23 DK099442NIDDK NIH HHS K23 DK100533
6 · The paper itself

Abstract

Patients with chronic kidney disease experience substantial loss of muscle mass, weakness, and poor physical performance. As kidney disease progresses, skeletal muscle dysfunction forms a common pathway for mobility limitation, loss of functional independence, and vulnerability to disease complications. Screening for those at high risk for mobility disability by self-reported and objective measures of function is an essential first step in developing an interdisciplinary approach to treatment that includes rehabilitative therapies and counseling on physical activity. Exercise has beneficial effects on systemic inflammation, muscle, and physical performance in chronic kidney disease. Kidney health providers need to identify patient and care delivery barriers to exercise in order to effectively counsel patients on physical activity. A thorough medical evaluation and assessment of baseline function using self-reported and objective function assessment is essential to guide an effective individualized exercise prescription to prevent function decline in persons with kidney disease. This review focuses on the impact of kidney disease on skeletal muscle dysfunction in the context of the disablement process and reviews screening and treatment strategies that kidney health professionals can use in clinical practice to prevent functional decline and disability.

Indexed as

ExerciseAgedExercise TherapyFrail ElderlyHand StrengthHumansKidney Failure, ChronicMaleMobility LimitationMuscle, SkeletalMuscle WeaknessPhysical EnduranceRenal Insufficiency, ChronicSarcopeniaWalk TestCKDESRDexercisefrailtyKidney diseasemusclemuscle dysfunctionolder adultsphysical functionpreventionrecommendations

Identifiers

PMID28427790
PMCPMC5441955
OpenAlexW2606066898

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.