Evidence map›Paper›PMID 28427473›Full record

ReviewPediatric rheumatology online journal2017

Intestinal Behçet and Crohn's disease: two sides of the same coin.

Simona Valenti, Romina Gallizzi, Dominique De Vivo, Claudio Romano

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Pediatric rheumatology online journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Simona ValentiUnit of Pediatrics, Department of Human Pathology in Adulthood and Childhood "G. Barresi", University of Messina, Viale Consolare Valeria, 98124, Messina, Italy.
Romina GallizziUnit of Pediatrics, Department of Human Pathology in Adulthood and Childhood "G. Barresi", University of Messina, Viale Consolare Valeria, 98124, Messina, Italy.
Dominique De VivoUnit of Pediatrics, Department of Human Pathology in Adulthood and Childhood "G. Barresi", University of Messina, Viale Consolare Valeria, 98124, Messina, Italy.
Claudio RomanoUnit of Pediatrics, Department of Human Pathology in Adulthood and Childhood "G. Barresi", University of Messina, Viale Consolare Valeria, 98124, Messina, Italy. romanoc@unime.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Behçet's disease (BD) and Crohn's disease (CD) are chronic immune-mediated, inflammatory disorders affecting many different systems (joints, skin, eyes, gastrointestinal and biliary tracts). Both disorders have fluctuating courses and when gastrointestinal symptoms are prevalent, differential diagnosis can be difficult. BD involves the gastrointestinal tract in 10-15% of cases with localized lesions in the ileocecal region. The clinical picture is heterogeneous with various clusters of disease expression. CD is a chronic inflammatory disorder, which can affect any part of the intestinal tract, as well as extra-intestinal tissue. Factors that contribute towards the pathogenesis of both disease include the host's genetic profile, and immune system, and environmental factors such as the gut microbiota. The aim of this manuscript is to provide a narrative review of clinical features of BD and CD, highlighting the importance of differential diagnosis and therapeutic approach, especially in the presence of gastrointestinal involvement. A comprehensive search of published literature using the Pubmed ( http://www.ncbi.nlm.nih.gov/pubmed/ ) database was carried out to identify all articles published in English from 1999 to October 2016, using 4 key terms: "Behçet Disease", "Intestinal Behçet's Disease", "Crohn's Disease" and" Inflammatory Bowel Disease".

Indexed as

Antirheumatic AgentsBehcet SyndromeCrohn DiseaseDiagnosis, DifferentialDigestive System Surgical ProceduresEndoscopy, GastrointestinalGastrointestinal DiseasesGout SuppressantsHumansImmunosuppressive AgentsAntirheumatic AgentsGout SuppressantsImmunosuppressive AgentsBehçet diseaseCrohn’s diseaseInflammatory bowel diseasesIntestinal Behçet disease

Identifiers

PMID28427473
PMCPMC5397832

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.