Evidence map›Paper›PMID 28427410›Full record

Trial reportRadiation oncology (London, England)2017

Long-term follow-up after stereotactic radiosurgery of intracanalicular acoustic neurinoma.

Daniel Rueß, Lea Pöhlmann, Stefan Grau, Christina Hamisch, Alexandra Hellerbach, Harald Treuer, Martin Kocher, Maximilian I Ruge

Abstract readClinical Trial
In one paragraph

Trial report in Radiation oncology (London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
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  6. Article
  7. Tumor control and hearing preservation after radiosurgery of intracanalicular vestibular schwannomas - systematic review.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2022
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
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  14. Twelve-year results of LINAC-based radiosurgery for vestibular schwannomas.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2020
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Daniel RueßDepartment of Stereotaxy and Functional Neurosurgery, Centre of Neurosurgery, University Hospital of Cologne, Kerpener Strasse 62, 50937, Köln, Germany. daniel.ruess@uk-koeln.de.
Lea PöhlmannDepartment of Stereotaxy and Functional Neurosurgery, Centre of Neurosurgery, University Hospital of Cologne, Kerpener Strasse 62, 50937, Köln, Germany.
Stefan GrauDepartment of General Neurosurgery, Centre of Neurosurgery, University Hospital of Cologne, Kerpener Strasse 62, Cologne, 50937, Germany.
Christina HamischDepartment of General Neurosurgery, Centre of Neurosurgery, University Hospital of Cologne, Kerpener Strasse 62, Cologne, 50937, Germany.
Alexandra HellerbachDepartment of Stereotaxy and Functional Neurosurgery, Centre of Neurosurgery, University Hospital of Cologne, Kerpener Strasse 62, 50937, Köln, Germany.
Harald TreuerDepartment of Stereotaxy and Functional Neurosurgery, Centre of Neurosurgery, University Hospital of Cologne, Kerpener Strasse 62, 50937, Köln, Germany.
Martin KocherDepartment of Radiation Oncology, University Hospital of Cologne, Kerpener Strasse 62, 50937, Cologne, Germany.
Maximilian I RugeDepartment of Stereotaxy and Functional Neurosurgery, Centre of Neurosurgery, University Hospital of Cologne, Kerpener Strasse 62, 50937, Köln, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe management of solely intracanalicular acoustic neurinoma (iAN) includes observation, microsurgical resection and radiation therapy. Treatment goals are long-term tumor control, hearing preservation and concurrently low side-effects. Stereotactic radiosurgery (SRS) has evolved as an alternative first-line treatment for small AN. Here we report about the long-term follow-up of a unique cohort of patients with iAN after LINAC or Cyberknife® based SRS.

methodsIn this single center retrospective analysis, we included all patients with iAN who underwent single session LINAC or Cyberknife® based SRS between 1993 and 2015, and who had a minimum follow-up period of six weeks. Patient data were analyzed in terms of radiological and clinical tumor control (no further treatment necessary), subjective preservation of serviceable hearing, objective change in pure tone averages (PTA), and adverse events rated by the Common Terminology Criteria for Adverse Events (CTCAE; v4.03).

resultsForty-nine patients (f/m = 21/28, median age 54 ± 12, range 20-77 years) were identified. Mean tumor volumes were 0.24 ± 0.12 cm

conclusionSRS for iAN shows long-term reliable tumor control with a high rate of hearing preservation without considerable permanent side effects, and can be proposed as a safe and effective treatment alternative to microsurgical resection.

Indexed as

RadiosurgeryAdultAgedEar CanalFemaleFollow-Up StudiesHumansMaleMiddle AgedNeoplasm Recurrence, LocalNeuroma, AcousticRadiation DosageRetrospective StudiesTreatment OutcomeTumor BurdenYoung Adult

Identifiers

PMID28427410
PMCPMC5399376

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.