ArticleBMC musculoskeletal disorders2017
Correlation between intervertebral disc degeneration, paraspinal muscle atrophy, and lumbar facet joints degeneration in patients with lumbar disc herniation.
Article in BMC musculoskeletal disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05245214 (Comprehensive Analysis Of Muscle Wasting In Disc Herniation), which is not on this map. Cited by 99 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comprehensive Analysis Of Muscle Wasting In Disc Herniation
Who cites it
99 citing papers in PubMed, 3 syntheses or guidelines pooled it, 159 citations in OpenAlex.
- Kinematics of the Cervical Spine Under Healthy and Degenerative Conditions: A Systematic Review.Annals of biomedical engineering · 2022Pooled it
- The association between changes in multifidus muscle morphology and back pain scores following discectomy surgery for lumbar disc herniation: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022Pooled it
- Relationships between paraspinal muscle morphology and neurocompressive conditions of the lumbar spine: a systematic review with meta-analysis.BMC musculoskeletal disorders · 2018Pooled it
- A clinical nomogram for predicting the residual low back pain after percutaneous endoscopic surgery for lumbar disc herniation.International orthopaedics · 2023Trial
- The effects of Pilates on pain, functionality, quality of life, flexibility and endurance in lumbar disc herniation.Journal of comparative effectiveness research · 2023Trial
- Article
- Association Between Degeneration of the Paraspinal Muscles and Nerve Root Compression in Lumbar Disc Herniation Patients Who Underwent Percutaneous Endoscopic Lumbar Discectomy.Orthopaedic surgery · 2026Article
- Machine Learning Model for Recurrent Lumbar Disc Herniation after Lumbar Discectomy.Journal of Korean Neurosurgical Society · 2026Article
- Preventing adjacent segment disease after lumbar fusion: a new perspective emphasizing individualized factors.Quantitative imaging in medicine and surgery · 2026Article
- Paravertebral muscle degeneration-guided selective fusion strategy for degenerative lumbar scoliosis: a novel approach to minimize surgical invasiveness while optimizing clinical outcomes.Frontiers in medicine · 2026Article
- Article
- Therapeutic Implants: Mechanobiologic Enhancement of Osteogenic, Angiogenic, and Myogenic Responses in Human Mesenchymal Stem Cells on 3D-Printed Titanium Truss.Advanced healthcare materials · 2025Article
- Paraspinal muscles and gluteus medius fat infiltration are both associated with lumbar disc herniation.Insights into imaging · 2025Article
- How to prevent preoperative adjacent segment degeneration L5/S1 segment occuring postoperative adjacent segment disease? A retrospective study of risk factor analysis.Journal of orthopaedic surgery and research · 2025Review
- Qualitative and quantitative characteristics of the lumbar multifidi muscles: Comparison of the magnetic resonance imaging and musculoskeletal ultrasound.Interventional pain medicine · 2025Article
- Analysis of factors associated with intercostal neuralgia after osteoporotic thoracic spine fracture and construction of a prediction model.BMC musculoskeletal disorders · 2025Article
- A Finite Element Study of Simulated Fusion in an L4-L5 Model: Influence of the Combination of Materials in the Screw-and-Rod Fixation System on Reproducing Natural Bone Behavior.Biomimetics (Basel, Switzerland) · 2025Article
- Article
- Are the facet joint parameters risk factors for cage subsidence after TLIF in patients with lumbar degenerative spondylolisthesis?European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024Article
- Acupuncture promotes neurological recovery and regulates lymphatic function after acute inflammatory nerve root injury.Heliyon · 2024Article
39 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo assess the correlation between lumbar disc degeneration (LDD), multifidus muscle atrophy (LMA), and facet joints degeneration in patients with L4-L5 lumbar disc herniation (LDH).
methodsSixty patients with L4-L5 LDH diagnosed by a 1.5 T MRI scanner were enrolled in the study group and another 60 patients with non-specific back pain were enrolled in the control group. LDD, LMA, and facet joints degeneration were examined and analyzed independently by two independent orthopedic surgeons using T2-weighted images. Wilcoxon test was used for analyzing the difference of LDD and facet joints degeneration between L3-L4 and L5-S1 and difference of LMA between the herniated and control groups. Correlation analysis of the three degeneration grades at the same level was determined by Spearman rank correlation test.
resultsIn the herniated group, most LMA at L3-L4 level was grade 1 (42, 70.0%); grade 2 (33, 55.0%) at L4-L5 level; and grade 3 (27, 45.0%) at L5-S1 level. LMA and LDD grading were significantly different between L3-L4 and L5-S1 levels (P < 0.05). In the herniation group, the Spearman value for LDD and LMA grading were 0.352 (P < 0.01) at L3-L4 and 0.036 (P > 0.05) at the L5-S1 level. The differences in LMA between the herniated and control groups at the three levels were significant (P < 0.05).
conclusionsDisc degeneration and multifidus muscles atrophy were positively correlated at the L3-L4 disc level. A lumbar extension muscle strengthening program could be helpful in preventing muscle atrophy and lumbar spinal degeneration.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.