ArticleOncotarget2017
Screening effective differential expression genes for hepatic carcinoma with metastasis in the peripheral blood mononuclear cells by RNA-seq.
Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 17 citations in OpenAlex.
- Single-cell profiling of peripheral and local immune compartments reveal unique genotype-independent prognostic immune signatures across isocitrate dehydrogenase-stratified glioma.Neuro-oncology · 2026Article
- Alternative splicing immune signature for detecting HBV-related hepatocellular carcinoma in peripheral blood mononuclear cells.Biochemistry and biophysics reports · 2025Article
- Identification of Three Key Genes Associated with Hepatocellular Carcinoma Progression Based on Co-expression Analysis.Cell biochemistry and biophysics · 2022Article
- Bioinformatics Study Revealed Significance of Exosome Transcriptome in Hepatocellular Carcinoma Diagnosis.Frontiers in cell and developmental biology · 2022Article
- CircRNA expression profiling of PBMCs from patients with hepatocellular carcinoma by RNA-sequencing.Experimental and therapeutic medicine · 2021Article
- Article
- Identification of BHLHE40 expression in peripheral blood mononuclear cells as a novel biomarker for diagnosis and prognosis of hepatocellular carcinoma.Scientific reports · 2021Article
- Identification of a protein signature for predicting overall survival of hepatocellular carcinoma: a study based on data mining.BMC cancer · 2020Article
- RainDrop: Rapid activation matrix computation for droplet-based single-cell RNA-seq reads.BMC bioinformatics · 2020Article
- High CENPM mRNA expression and its prognostic significance in hepatocellular carcinoma: a study based on data mining.Cancer cell international · 2020Article
- Alevin efficiently estimates accurate gene abundances from dscRNA-seq data.Genome biology · 2019Article
- Expression And Biological Interaction Network Of RHOC For Hepatic Carcinoma With Metastasis In PBMC Samples.OncoTargets and therapy · 2019Article
- BioMuta and BioXpress: mutation and expression knowledgebases for cancer biomarker discovery.Nucleic acids research · 2018Article
- Identifying Potential New Gene Expression-Based Biomarkers in the Peripheral Blood Mononuclear Cells of Hepatitis B-Related Hepatocellular Carcinoma.Canadian journal of gastroenterology & hepatologyArticle
- Single sample scoring of hepatocellular carcinoma: A study based on data mining.International journal of immunopathology and pharmacologyArticle
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tumor metastasis is a multistep process involving a number of genetic alterations so that the genetic diagnosis is got increasingly attentions today. The aim of this study was to use RNA-seq to screen the effective differential expression genes in the peripheral blood mononuclear cells for the hepatic carcinoma with metastasis. The results showed that hepatic carcinoma samples gathered according to different metastasis. CCL3, CCL3L1, JUN, IL8, and IL1B were identified in inflammation mediated by chemokine and cytokine signaling pathway (P00031) in the hepatic carcinoma samples with metastasis, and subsequently confirmed by quantitative real-time polymerase chain reaction. In conclusions, CCL3, CCL3L1, JUN, IL8, and IL1B have the potential to be considered as candidates for future molecular diagnosis of the hepatic carcinoma with metastasis. This work may provide us with new visions into the metastasis process and potential efficient clinical diagnosis in the future.
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